Secondary Logo

Journal Logo

Current World Literature

Current Opinion in Lipidology: April 2009 - Volume 20 - Issue 2 - p 135–142
doi: 10.1097/MOL.0b013e32832a7e09
Current World Literature: Bibliography
Free

This bibliography is compiled by clinicians from the journals listed at the end of this publication. It is based on literature entered into our database between 1 December 2007 and 30 November 2008 (articles are generally added to the database about two and a half months after publication). In addition, the bibliography contains every paper annotated by reviewers; these references were obtained from a variety of bibliographic databases and published between the beginning of the review period and the time of going to press. The bibliography has been grouped into topics that relate to the reviews in this issue.

• Papers considered by the reviewers to be of special interest

•• Papers considered by the reviewers to be of outstanding interest

The number in square brackets following a selected paper, e.g. [7], refers to its number in the annotated references of the corresponding review.

Back to Top | Article Outline

Genetics and molecular biology

Genome-wide association study for type 2 diabetes: clinical applications

Review: (pp. 87–91)

Andersen G, Burgdorf KS, Sparso T, Borch-Johnsen K, et al. AHSG tag single nucleotide Polymorphisms associate with type 2 diabetes and dyslipidemia: Studies of metabolic traits in 7,683 white danish subjects. Diabetes 2008; 57:1427–1432.

Florez JC, Manning AK, Dupuis J, McAteer J, et al. A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study. Diabetes 2007; 56:3063–3074.

Freedman BI, Bowden DW, Rich SS, Xu J, et al. Genome-wide linkage scans for renal function and albuminuria in Type 2 diabetes mellitus: the Diabetes Heart Study. Diabet Med 2008; 25:268–276.

Grarup N, Rose CS, Andersson EA, Andersen G, et al. Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects - Validation and extension of genome-wide association studies. Diabetes 2007; 56:3105–3111.

Hakonarson H, Qu HQ, Bradfield JP, Marchand L, et al. A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. Diabetes 2008; 57:1143–1146.

Hayes MG, Pluzhnikov A, Miyake K, Sun Y, et al. Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies. Diabetes 2007; 56:3033–3044.

Hertel JK, Johansson S, Raeder H, Midthjell K, et al. Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study). Diabetologia 2008; 51:971–977.

Holmkvist J, Anthonsen S, Wegner L, Andersen G, et al. Polymorphisms in AHI1 are not associated with type 2 diabetes or related phenotypes in Danes: non-replication of a genome-wide association result. Diabetologia 2008; 51:609–614.

Johansson S, Roeder H, Eide SA, Midthjell K, et al. Studies in 3,523 Norwegians and meta-analysis in 11,571 subjects indicate that variants in the hepatocyte nuclear factor 4 alpha (HNF4A) P2 region are associated with type 2 diabetes in Scandinavians. Diabetes 2007; 56:3112–3117.

Jongjaroenprasert W, Chanprasertyothin S, Kongsuksai A, Bunnag P, et al. Association of genetic variations near P2 promoter of the hepatocyte nuclear factor-4 alpha gene and insulin secretion index in Thais. Acta Diabetol 2007; 44:227–232.

•• Kathiresan S, Melander O, Anevski D, et al. Polymorphisms associated with cholesterol and risk of cardiovascular events. N Engl J Med 2008; 358:1240–1249.[38]

Kondkar AA, Nair KG, Ashavaid TF. Genetic analysis of Indian subjects with clinical features of possible type IIa hypercholesterolemia. J Clin Lab Anal 2007; 21:375–381.

Kronenberg F. Genome-wide association studies in aging-related processes such as diabetes mellitus, atherosclerosis and cancer [Review]. Exp Gerontol 2008; 43:39–43.

Li MZ, Yu DM, Yu P, Liu DM, et al. Mitochondrial gene mutations and type 2 diabetes in Chinese families. Chin Med J 2008; 121:682–686.

•• Link E, Parish S, Armitage J, et al. SLCO1B1 variants and statin-induced myopathy: a genomewide study. N Engl J Med 2008; 359:789–799.[40]

•• Lyssenko V, Jonsson A, Almgren P, et al. Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med 2008; 359:2220–2232.[08]

•• Lyssenko V, Nagorny CL, Erdos MR, et al. Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet 2009; 41:82–88.[25]

Martens FMAC, van der Graaf Y, Dijk JA, Olijhoek JK, et al. Carotid arterial stiffness is marginally higher in the metabolic syndrome and markedly higher in type 2 diabetes mellitus in patients with manifestations of arterial disease. Atherosclerosis 2008; 197:646–653.

New JP, Aung T, Baker PG, Yongsheng G, et al. The high prevalence of unrecognized anaemia in patients with diabetes and chronic kidney disease: a population-based study. Diabet Med 2008; 25:564–569.

•• No Authors Given. Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research, Saxena R, Voight BF, Lyssenko V, et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007; 316:1331–1336.[11]

•• Prokopenko I, Langenberg C, Florez JC, et al. Variants in MTNR1B influence fasting glucose levels. Nat Genet 2009; 41:77–81.[26]

Rampersaud E, Damcott CM, Fu M, Shen HQ, et al. Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the old order Amish. Diabetes 2007; 56:3053–3062.

•• Scott LJ, Mohlke KL, Bonnycastle LL, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007; 316:1341–1345.[12]

Tuomilehto H, Peltonen M, Partinen M, Seppa J, et al. Sleep-disordered breathing is related to an increased risk for type 2 diabetes in middle-aged men, but not in women - the FIN-D2D survey. Diabetes Obes Metab 2008; 10.

•• Zeggini E, Weedon MN, Lindgren CM, et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007; 316:1336–1341.[15]

Back to Top | Article Outline

Optimal designs for replicating genome-wide association studies

Feng T, Zhang SL, Sha QY. Two-stage association tests for genome-wide association studies based on family data with arbitrary family structure. Eur J Human Genet 2007; 15:1169–1175.

Grarup N, Rose CS, Andersson EA, Andersen G, et al. Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects - Validation and extension of genome-wide association studies. Diabetes 2007; 56:3105–3111.

Gu CC, Yu K, Ketkar S, Templeton AR, et al. On transferability of genome-wide tagSNPs [Review]. Genet Epidemiol 2008; 32:89–97.

Hoggart CJ, Clark TG, De Lorio M, Whittaker JC, et al. Genome-wide significance for dense SNP and resequencing data. Genet Epidemiol 2008; 32:179–185.

Kokko H, Heubel K. Condition-dependence, genotype-by-environment interactions and the lek paradox. Genetica 2008; 132:209–216.

Leanza SM, Burk RD, Rohan TE. Whole genome amplification of DNA extracted from hair samples: Potential for use in molecular epidemiologic studies. Cancer Detect Prev 2007; 31:480–488.

Li MY, Li C, Guan W. Evaluation of coverage variation of SNP chips for genome-wide association studies. Eur J Human Genet 2008; 16:635–643.

Li QZ, Yu K. Improved correction for population stratification in genome-wide association studies by identifying hidden population structures. Genet Epidemiol 2008; 32:215–226.

Luca D, Ringquist S, Klei L, Lee AB, et al. On the use of general control samples for genome-wide association studies: Genetic matching highlights causal variants. Am J Hum Genet 2008; 82:453–463.

Medeiros F, Rigl CT, Anderson GG, Becker SH, et al. Tissue handling for genome-wide expression analysis - A review of the issues, evidence, and opportunities [Review]. Arch Pathol Lab Med 2007; 131:1805–1816.

Pearson TA, Manolio TA. How to interpret a genome-wide association study. JAMA 2008; 299:1335–1344.

Petremand J, Abderrahmani A, Widmann C. Genetics and molecular biology: HDLs and their multiple ways to protect cells. Curr Opin Lipidol 2008; 19:95–97.

Pickrell J, Clerget-Darpoux F, Bourgain C. Power of genome-wide association studies in the presence of interacting loci. Genet Epidemiol 2007; 31:748–762.

Rieder MJ, Livingston RJ, Stanaway IB, Nickerson DA. The Environmental Genome Project: Reference polymorphisms for drug metabolism genes and genome-wide association studies [Review]. Drug Metab Rev 2008; 40:241–261.

Roeder K, Devlin B, Wasserman L. Improving power in genome-wide association studies: Weights tip the scale. Genet Epidemiol 2007; 31:741–747.

Seng KC, Seng CK. The success of the genome-wide association approach: a brief story of a long struggle [Review]. Eur J Human Genet 2008; 16:554–564.

Skoll AD, Scott LJ, Abecasis GR, Boehnke M. Optimal designs for two-stage genome-wide association studies. Genet Epidemiol 2007; 31:776–788.

Teo YY. Common statistical issues in genome-wide association studies: a review on power, data quality control, genotype calling and population structure [Review]. Curr Opin Lipidol 2008; 19:133–143.

Tremelling M, Parkes M. Genome-wide association scans identify multiple confirmed susceptibility loci for Crohn's disease: Lessons for study design [Review]. Inflamm Bowel Dis 2007; 13:1554–1560.

Visscher PM, Andrew T, Nyholt DR. Genome-wide association studies of quantitative traits with related individuals: little (power) lost but much to be gained. Eur J Human Genet 2008; 16:387–390.

Back to Top | Article Outline

Aging, lipids and genetics

Kronenberg F. Genome-wide association studies in aging-related processes such as diabetes mellitus, atherosclerosis and cancer [Review]. Exp Gerontol 2008; 43:39–43.

Lopez-Miranda J, Williams C, Lairon D. Dietary, physiological, genetic and pathological influences on postprandial lipid metabolism [Review]. Br J Nutr 2007; 98:458–473.

Manolagas SC, Almeida M. Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism [Review]. Mol Endocrinol 2007; 21:2605–2614.

Marchegiani F, Marra M, Olivieri F, Cardelli M, et al. Paraoxonase 1: Genetics and activities during aging [Review]. Rejuv Res 2008; 11:113–127.

Parsons JK, Bergstrom J, Barrett-Connor E. Lipids, lipoproteins and the risk of benign prostatic hyperplasia in community-dwelling men. BJU Int 2008; 101:313–318.

Rodrigues AC, Hirata MH, Hirata RD. The genetic determinants of atorvastatin response [Review]. Curr Opin Mol Ther 2007; 9:545–553.

Rosa JS, Oliver SR, Mitsuhashi M, Flores RL, et al. Altered kinetics of interleukin-6 and other inflammatory mediators during exercise in children with type 1 diabetes. J Invest Med 2008; 56:701–713.

Yoshida T, Yajima K, Hibino T, Kato K, et al. Association of gene polymorphisms with myocardial infarction in individuals with different lipid profiles. Int J Mol Med 2007; 20:581–590.

Zeller M, Masson D, Farnier M, Lorgis L, et al. High serum cholesteryl ester transfer rates and small high-density lipoproteins are associated with young age in patients with acute myocardial infarction. J Am Coll Cardiol 2007; 50:1948–1955.

Back to Top | Article Outline

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

Review: (pp. 98–105)

• Banks AS, Kon N, Knight C, et al. SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab 2008; 8:333–341.[79]

• Chen D, Bruno J, Easlon E, et al. Tissue-specific regulation of SIRT1 by calorie restriction. Genes Dev 2008; 22:1753–1757.[82]

•• Coste A, Louet JF, Lagouge M, et al. The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proc Natl Acad Sci U S A 2008; 105:17187–17192.[73]

• Garcia-Roves PM, Osler ME, Holmstrom MH, Zierath JR. Gain-of-function R225Q mutation in AMP-activated protein kinase gamma 3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle. J Biol Chem 2008; 283:35724–35734.[90]

• Handschin C, Chin S, Li P, et al. Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals. J Biol Chem 2007; 282:30014–30021.[33]

Hipkiss AR. Energy metabolism, altered proteins, sirtuins and ageing: Converging mechanisms? Biogerontology 2008; 9:49–55.

• Jager S, Handschin C, St-Pierre J, Spiegelman BM. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A 2007; 104:12017–12022.[50]

• Liu Y, Dentin R, Chen D, et al. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature 2008; 456:269–273.[76]

Saji T, Kikuchi R, Kusuhara H, Kim I, et al. Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/beta. J Pharmacol Exp Ther 2008; 324:784–790.

Seedorf U, Aberle J. Emerging roles of PPAR delta in metabolism [Review]. Biochim Biophys Acta Mol Cell Biol Lipids 2007; 1771:1125–1131.

Yamada Y, Matsuo H, Warita S, Watanabe S, et al. Prediction of genetic risk for dyslipidemia. Genomics 2007; 90:551–558.

Back to Top | Article Outline

Genetics of energy balance

Cai G, Cole SA, Butte NF, Voruganti VS, et al. Genome-wide scan revealed genetic loci for energy metabolism in Hispanic children and adolescents. Int J Obes 2008; 32:579–585.

Back to Top | Article Outline

Resolving complex diseases in complex populations

Cakir M, Akcay S, Karakas T, Gedik Y, et al. Prevalence of atopy in children with type 1 diabetes mellitus, hepatitis B virus carriers, and healthy children: Role of T helper 1 (Th1)-type immune response. Allergy Asthma Proc 2008; 29:166–170.

Ebersole JL, Holt SC, Hansard R, Novak MJ. Microbiologic and immunologic characteristics of periodontal disease in Hispanic Americans with type 2 diabetes. J Periodontol 2008; 79:637–646.

Elkeles RS, Godsland IF, Rubens MB, Feher MD, et al. The progress of coronary heart disease in Type 2 diabetes as measured by coronary calcium score from electron beam computed tomography (EBCT): The PREDICT study. Atherosclerosis 2008; 197:777–783.

Gottlieb AB, Chao C, Dann F. Psoriasis comorbidities [Review]. J Dermatol Treatment 2008; 19:5–21.

Kondkar AA, Nair KG, Ashavaid TF. Genetic analysis of Indian subjects with clinical features of possible type IIa hypercholesterolemia. J Clin Lab Anal 2007; 21:375–381.

Lindemann K, Vatten LJ, Ellstrom-Engh M, Eskild A. Body mass, diabetes and smoking, and endometrial cancer risk: a follow-up study. Br J Cancer 2008; 98:1582–1585.

Novak MJ, Potter RM, Blodgett J, Ebersole JL. Periodontal disease in Hispanic Americans with type 2 diabetes. J Periodontol 2008; 79:629–636.

Remes-Troche JM, Rios-Vaca A, Ramirez-Iglesias MT, Rubio-Tapia A, et al. High prevalence of celiac disease in Mexican mestizo adults with type 1 diabetes mellitus. J Clin Gastroenterol 2008; 42:460–465.

Salardi S, Volta U, Zucchini S, Fiorini E, et al. Prevalence of celiac disease in children with type 1 diabetes mellitus increased in the mid-1990s: An 18-year longitudinal study based on anti-endomysial antibodies. J Pediatr Gastroenterol Nutr 2008; 46:612–614.

Villarroya F, Domingo P, Giralt M. Lipodystrophy in HIV 1-infected patients: lessons for obesity research [Review]. Int J Obes 2007; 31:1763–1776.

Back to Top | Article Outline

Hepatic nuclear factor 1-α,: inflammation, genetics and atherosclerosis

Review: (pp. 106–111)

• Casas JP, Shah T, Hingorani AD, et al. C-reactive protein and coronary heart disease: a critical review. J Int Med 2008; 264:295–314.[05]

Furihata T, Satoh T, Yamamoto N, Kobayashi K, et al. Hepatocyte nuclear factor 1 alpha is a factor responsible for the interindividual variation of OATP1B1 mRNA levels in adult Japanese livers. Pharm Res 2007; 24:2327–2332.

• Geier A, Wagner M, Dietrich CG, Trauner M. Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration. Biochim Biophys Acta 2007; 1773:283–308.[57]

• Hage FG, Szalai AJ. C-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk. J Am Coll Cardiol 2007; 50:1115–1122.[24]

•• Kathiresan S, Willer CJ, Peloso GM, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009; 41:56–65.[27]

Kikuchi R, Kusuhara H, Hattori N, Kim I, et al. Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation. Mol Pharmacol 2007; 72:1619–1625.

• Lawlor DA, Harbord RM, Timpson NJ, et al. The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4610 cases amongst 18 637 participants. PLoS One 2008; 3:e3011.[08]

Mayer C, Bottcher Y, Kovacs P, Halbriitter J, et al. Phenotype of a patient with a de novo mutation in the hepatocyte nuclear factor 1 beta/maturity-onset diabetes of the young type 5 gene. Metab-Clin Exp 2008; 57:416–420, 2008 Mar.

• Nishikawa T, Hagihara K, Serada S, et al. Transcriptional complex formation of c-Fos, STAT3, and hepatocyte NF-1 alpha is essential for cytokine-driven C-reactive protein gene expression. J Immunol 2008; 180:3492–3501.[52]

• Packard RR, Libby P. Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin Chem 2008; 54:24–38.[02]

Ramirez J, Mirkov S, Zhang W, Chen P, et al. Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver. Pharmacogenomics J 2008; 8:152–161.

•• Reiner AP, Barber MJ, Guan Y, et al. Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. Am J Hum Genet 2008; 82:1193–1201.[09]

• Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 2008; 359:2195–2207.[17]

•• Ridker PM, Pare G, Parker A, et al. Loci related to metabolic-syndrome pathways including LEPR, HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study. Am J Hum Genet 2008; 82:1185–1192.[10]

• Schunkert H, Samani NJ. Elevated C-reactive protein in atherosclerosis – chicken or egg? N Engl J Med 2008; 359:1953–1955.[07]

Back to Top | Article Outline

Developmental pathways to obesity and dyslipidemia: the role of epigenetics

Barness LA, Opitz JM, Gilbert-Barness E. Obesity: Genetic, molecular, and environmental aspects. Am J Med Genet 2007; 143A:3016–3034.

Faith MS, Rhea SA, Corley RP, Hewitt JK. Genetic and shared environmental influences on children's 24-h food and beverage intake: sex differences at age 7 y. Am J Clin Nutr 2008; 87:903–911.

Jeyakumar SM, Vajreswari A, Giridharan NV. Vitamin A regulates obesity in WNIN/Ob obese rat; independent of stearoyl-CoA desaturase-1. Biochem Biophys Res Commun 2008; 370:243–247.

Kang YX, Li M, Yan WQ, Li XJ, et al. Electroacupuncture alters the expression of genes associated with lipid metabolism and immune reaction in liver of hypercholesterolemia mice. Biotechnol Lett 2007; 29:1817–1824.

Li TY, Zhang C, Asselbergs FW, Qi L, et al. Interaction between dietary fat intake and the cholesterol ester transfer protein TaqlB polymorphism in relation to HDL-cholesterol concentrations among US diabetic men. Am J Clin Nutr 2007; 86:1524–1529.

Murakami T, Walczak R, Caron S, Duhem C, et al. The farnesoid X receptor induces fetuin-B gene expression in human hepatocytes. Biochem J 2007; 407:461–469.

Prainfalk C, Angelin B, Eriksson M, Parini P. Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells. Biochem Biophys Res Commun 2007; 364:402–409.

Romao I, Roth J. Genetic and environmental interactions in obesity and type 2 diabetes [Review]. J Am Diet Assoc 2008; 108:S24–S28.

Back to Top | Article Outline

Genome-wide association studies for other diseases

Abe T, Fukushima N, Brune K, Boehm C, et al. Genome-wide allelotypes of familial pancreatic adenocarcinomas and familial and sporadic intraductal papillary mucinous neoplasms. Clin Cancer Res 2007; 13:6019–6025.

Ambrosone CB. The promise and limitations of genome-wide association studies to elucidate the causes of breast cancer - art. no. 114. Breast Cancer Research 2007; 9:114.

Bae S, Ha TS, Yoon Y, Lee J, et al. Genome-wide screening and identification of novel proteolytic cleavage targets of caspase-8 and -10 in vitro. Int J Mol Med 2008; 21:381–386.

Blcuw HM, Veldink JH, van Es MA, van Vught PW, et al. Copy-number variation in sporadic amyotrophic lateral scleroses: a genome-wide screen. Lancet Neurol 2008; 7:319–326.

Boomsma DI, Willemsen G, Sullivan PF, Heutink P, et al. Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects. Eur J Human Genet 2008; 16:335–342.

Byun E, Caillier SJ, Montalban X, Villoslada P, et al. Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis. Arch Neurol 2008; 65:337–E2.

Cai G, Cole SA, Butte NF, Voruganti VS, et al. Genome-wide scan revealed genetic loci for energy metabolism in Hispanic children and adolescents. Int J Obes 2008; 32:579–585.

Daley D, Lewis S, Platzer P, MacMillen M, et al. Identification of susceptibility genes for cancer in a genome-wide scan: Results from the colon neoplasia sibling study. Am J Hum Genet 2008; 82:723–736.

De Mars G, Windelinckx A, Huygens W, Peeters MW, et al. Genome-wide linkage scan for maximum and length-dependent knee muscle strength in young men: significant evidence for linkage at chromosome 14q24.3. J Med Genet 2008; 45:275–283.

Everett KV, Chioza BA, Georgoula C, Reece A, et al. Genome-wide high-density SNP-based linkage analysis of infantile hypertrophic pyloric stenosis identifies loci on chromosomes 11ql4-q22 and xq23. Am J Hum Genet 2008; 82:756–762.

Forconi F, Poretti G, Kwee I, Sozzi E, et al. High density genome-wide DNA profiling reveals a remarkably stable profile in hairy cell leukaemia. Br J Haematol 2008; 141:622–630.

Franceschini N, MacCluer JW, Rose KM, Rutherford S, et al. Genome-wide linkage analysis of pulse pressure in American Indians: The strong heart study. Am J Hypertens 2008; 21:194–199.

Horne BD, Carlquist JF, Muhlestein JB, Nicholas ZP, et al. Associations with myocardial infarction of six polymorphisms selected from a three-stage genome-wide association study. Am Heart J 2007; 154:969–975.

Inada T, Koga M, Ishiguro H, Horiuchi Y, et al. Pathway-based association analysis of genome-wide screening data suggest that genes associated with the gamma-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia. Pharmacogenet Genomics 2008; 18:317–323.

Kayser M, Liu F, Cecile A, Janssens JW, et al. Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene. Am J Hum Genet 2008; 82:411–423.

Kelly H, Molony CM, Darlow JM, Pirker ME, et al. A genome-wide scan for genes involved in primary vesicoureteric reflux. J Med Genet 2007; 44:710–717.

Kronenberg F. Genome-wide association studies in aging-related processes such as diabetes mellitus, atherosclerosis and cancer [Review]. Exp Gerontol 2008; 43:39–43.

Leanza SM, Burk RD, Rohan TE. Whole genome amplification of DNA extracted from hair samples: Potential for use in molecular epidemiologic studies. Cancer Detect Prev 2007; 31:480–488.

Linsel-Nitschke P, Schunkert H, Erdmann J. Congestive heart failure is a common disease with complex inheritance - new perspectives through genome wide association studies [German]. Internist (Berl) 2008; 49:405.

Lu XS, Lu X, Wang ZCG, Iglehart JD, et al. Predicting features of breast cancer with gene expression patterns. Breast Cancer Res Treat 2008; 108:191–201.

McCabe CD, Spyropoulos DD, Martin D, Moreno CS. Genome-wide analysis of the homeobox C6 transcriptional network in prostate cancer. Cancer Res 2008; 68:1988–1996.

Meng Y, Lee JH, Cheng R, George-Hyslop P, et al. Association between SORLI and Alzheimer's disease in a genome-wide study. Neuroreport 2007; 18:1761–1764.

Middeldorp CM, Hottenga JJ, Slagboom PE, Sullivan PF, et al. Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype. Mol Psychiatr 2008; 13:84–89.

Petremand J, Abderrahmani A, Widmann C. Genetics and molecular biology: HDLs and their multiple ways to protect cells. Curr Opin Lipidol 2008; 19:95–97.

Richards JB, Rivadeneira F, Inouye M, Pastinen TM, et al. Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study. Lancet 2008; 371:1505–1512.

Rieder MJ, Livingston RJ, Stanaway IB, Nickerson DA. The Environmental Genome Project: Reference polymorphisms for drug metabolism genes and genome-wide association studies [Review]. Drug Metab Rev 2008; 40:241–261.

Romanos M, Freitag C, Jacob C, Craig DW, et al. Genome-wide linkage analysis of ADHD using high-density SNP arrays: novel loci at 5q13.1 and 14q12. Mol Psychiatr 2008; 13:522–530.

Sandhu MS, Waterworth DM, Debenham SL, Wheeler E, et al. LDL-cholesterol concentrations: a genome-wide association study. Lancet 2008; 371:483–491.

Sellick GS, Goldin LR, Wild RW, Slager SL, et al. A high-density SNP genome-wide linkage search of 206 families identifies susceptibility loci for chronic lymphocytic leukemia. Blood 2007; 110:3326–3333.

Suzuki S, Yoshimura M, Nakayama M, Abe K, et al. A novel genetic marker for coronary spasm in women from a genome-wide single nucleotide polymorphism analysis. Pharmacogenet Genomics 2007; 17:919–930.

Tallon-Walton V, Manzanares-Cespedes MC, Arte S, Carvalho-Lobato P, et al. Identification of a novel mutation in the PAX9 gene in a family affected by oligodontia and other dental anomalies. Eur J Oral Sci 2007; 115:427–432.

Uhl GR, Drgon T, Liu QR, Johnson C, et al. Genome-wide association for methamphetamine dependence. Arch Gen Psychiatry 2008; 65:345–355.

Wallace C, Newhouse SJ, Braund P, Zhang F, et al. Genome-wide association study identifies genes for biomarkers of cardiovascular disease: Serum urate and dyslipiclemia. Am J Hum Genet 2008; 82:139–149.

Waring SC, Rosenberg RN. Genome-wide association studies in Alzheimer disease [Review]. Arch Neurol 2008; 65:329–334.

Back to Top | Article Outline

Cardiovascular disease: genetics and risk factors

Asimakopoulou KG, Skinner TC, Spimpolo J, Marsh S, et al. Unrealistic pessimism about risk of coronary heart disease and stroke in patients with type 2 diabetes. Patient Educ Counseling 2008; 71:95–101.

Bellocchio L, Vicennati V, Cervino C, Pasquali R, et al. The endocannabinoid system in the regulation of cardiometabolic risk factors [Review]. Am J Cardiol 2007; 100:7P–17P.

Franceschini N, MacCluer JW, Rose KM, Rutherford S, et al. Genome-wide linkage analysis of pulse pressure in American Indians: The strong heart study. Am J Hypertens 2008; 21:194–199.

Gladfelter AS, Montagna C. Seeking truth on Monte verita - Workshop on the molecular biology and biochemistry of septins and septin function. Embo Rep 2007; 8:1120–1126.

Horne BD, Carlquist JF, Muhlestein JB, Nicholas ZP, et al. Associations with myocardial infarction of six polymorphisms selected from a three-stage genome-wide association study. Am Heart J 2007; 154:969–975.

Hurrell C, Wietlisbach V, Jotterand V, Volet M, et al. High prevalence of major cardiovascular risk factors in first-degree relatives of individuals with familial premature coronary artery disease - The GENECARD project. Atherosclerosis 2007; 194:253–264.

Kamide K, Kokubo Y, Fukuhara S, Hanada H, et al. Protein tyrosine kinase 2 beta as a candidate gene for hypertension. Pharmacogenet Genomics 2007; 17:931–939.

Linsel-Nitschke P, Schunkert H, Erdmann J. Congestive heart failure is a common disease with complex inheritance - new perspectives through genome wide association studies [German]. Internist (Berl) 2008; 49:405.

Niemiec P, Zak I, Wita K. The 242 T variant of the CYBA gene polymorphism increases the risk of coronary artery disease associated with cigarette smoking and hypercholesterolemia (vol 18, pg 339, 2007). Coron Artery Dis 2007; 18:587.

Rivero K, Portal VL, Vieira M, Behle I. Prevalence of the impaired glucose metabolism and its association with risk factors for coronary artery disease in women with gestational diabetes. Diabetes Res Clin Pract 2008; 79:433–437.

Rodrigues AC, Hirata MH, Hirata RD. The genetic determinants of atorvastatin response [Review]. Curr Opin Mol Ther 2007; 9:545–553.

Scartezini M, Hubbart C, Whittall RA, Cooper JA, et al. The PCSK9 gene R46L variant is associated with lower plasma lipid levels and cardiovascular risk in healthy UK men. Clin Sci (Colch) 2007; 113:435–441.

Tosi I, Toledo-Leiva P, Neuwirth C, Naoumova RP, et al. Genetic defects causing familial hypercholesterolaemia: Identification of deletions and duplications in the LDL-receptor gene and summary of all mutations found in patients attending the Hammersmith Hospital lipid clinic. Atherosclerosis 2007; 194:102–111.

Wallace C, Newhouse SJ, Braund P, Zhang F, et al. Genome-wide association study identifies genes for biomarkers of cardiovascular disease: Serum urate and dyslipiclemia. Am J Hum Genet 2008; 82:139–149.

Yoshida T, Yajima K, Hibino T, Kato K, et al. Association of gene polymorphisms with myocardial infarction in individuals with different lipid profiles. Int J Mol Med 2007; 20:581–590.

Back to Top | Article Outline

Atherosclerosis: genetics and molecular pathology

Doran DE, Weiss D, Zhang Y, Griendling KK, et al. Differential effects of AT(1) receptor and Ca2+ channel blockade on atherosclerosis, inflammatory gene expression, and production of reactive oxygen species. Atherosclerosis 2007; 195:39–47.

Hansen MK, Connolly TM. Nuclear receptors as drug targets in obesity, dyslipidemia and atherosclerosis [Review]. Curr Opin Investig Drugs 2008; 9:247–255.

Heinonen SE, Leppanen P, Kholova I, Lumivuori H, et al. Increased atherosclerotic lesion calcification in a novel mouse model combining insulin resistance, hyperglycemia, and Hypercholesterolemia. Circ Res 2007; 101:1058–1067.

Jagavelu K, Tietge UJF, Gaestel M, Drexler H, et al. Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice. Circ Res 2007; 101:1104–1112.

Kang XQ, Song ZY, McClain CJ, Kang YJ, et al. Zinc supplementation enhances hepatic regeneration by preserving hepatocyte nuclear factor-4 alpha in mice subjected to long-term ethanol administration. Am J Pathol 2008; 172:916–925.

King VL, Cassis LA, Daugherty A. Interleukin-4 does not influence development of hypercholesterolemia or angiotensin II-induced atherosclerotic lesions in mice. Am J Pathol 2007; 171:2040–2047.

Klement H, Croix BS, Milsom C, May L, et al. Atherosclerosis and vascular aging as modifiers of tumor progression, angiogenesis, and responsiveness to therapy. Am J Pathol 2007; 171:1342–1351.

Krohn R, Raffetseder U, Bot I, Zerneeke A, et al. Y-box binding protein-1 controls CC chemokine ligand-5 (CCL5) expression in smooth muscle cells and contributes to neointima formation in atherosclerosis-prone mice. Circulation 2007; 116:1812–1820.

Lin MS, Hsu HC, Lin LC, Li HY, et al. Higher glutathione peroxidase expression in thoracic aorta as a protective factor against oxidative stress and atherosclerosis in rabbits. Cardiology 2007; 108:381–386.

Maeda N, Johnson L, Kim S, Hagaman J, et al. Anatomical differences and atherosclerosis in apolipoprotein E-deficient mice with 129/SvEv and C57BL/6. Atherosclerosis 2007; 195:75–82.

Rizvi AA. Inflammation markers as mediators of vasculo-endothelial dysfunction and atherosclerosis in the metabolic syndrome and type 2 diabetes. Chin Med J 2007; 120:1918–1924.

Wang SS, Shi WB, Wang XP, Velky L, et al. Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice. Arterioscler Thromb Vasc Biol 2008; 27.

Won D, Zhu SN, Chen M, Teichert AM, et al. Relative reduction of endothelial nitric-oxide synthase expression and transcription in atherosclerosis-prone regions of the mouse aorta and in an in Vitro model of disturbed flow. Am J Pathol 2007; 171:1691–1704.

Back to Top | Article Outline

Hepatocyte nuclear factors

Anandakrishnan R, Onufriev A. Analysis of basic clustering algorithms for numerical estimation of statistical averages in biomolecules. J Comput Biol 2008; 15:165–184.

Edghill EL, Oram RA, Owens M, Stals KL, et al. Hepatocyte nuclear factor-1 beta gene deletions - a common cause of renal disease. Nephrol Dial Transplant 2008; 23:627–635.

Faguer S, Bouissou F, Dumazer P, Guitard J, et al. Massively enlarged polycystic kidneys in monozygotic twins with TCF2/HNF-1 beta (hepatocyte nuclear factor-1 beta) heterozygous whole-gene deletion. Am J Kidney Dis 2007; 50:1023–1027.

Fajans SS, Bell GI. Macrosomia and neonatal hypoglycaemia in RW pedigree subjects with a mutation (Q268X) in the gene encoding hepatocyte nuclear factor 4 alpha (HNF4A). Diabetologia 2007; 50:2600–2601.

Fang HL, Strom SC, Ellis E, Duanmu Z, et al. Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: Roles of hepatocyte nuclear factor 4 alpha and pregnane X receptor. J Pharmacol Exp Ther 2007; 323:586–598.

Goodyer CG, Rhani Z, Zheng H. Expression of the hepatic specific V1 messenger ribonucleic acid of the human growth hormone receptor gene is regulated by hepatic nuclear factor (HNF)-4 alpha 2 and HNF-4 alpha 8. Mol Endocrinol 2008; 22:485–500.

Hara M, Shen J, Pugh W, Polonsky KS, et al. Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis. Exp Clin Endocrinol Diabetes 2007; 115:654–661.

Holloway MG, Miles GD, Dombkowski AA, Waxman DJ. Liver-specific hepatocyte nuclear factor-4 alpha deficiency: Greater impact on gene expression in male than in female mouse liver. Mol Endocrinol 2008; 22:1274–1286.

Hwang-Verslues WW, Sladek FM. Nuclear receptor hepatocyte nuclear factor 4 alpha 1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter. Mol Endocrinol 2008; 22:78–90.

Johansson S, Roeder H, Eide SA, Midthjell K, et al. Studies in 3,523 Norwegians and meta-analysis in 11,571 subjects indicate that variants in the hepatocyte nuclear factor 4 alpha (HNF4A) P2 region are associated with type 2 diabetes in Scandinavians. Diabetes 2007; 56:3112–3117.

Kang XQ, Song ZY, McClain CJ, Kang YJ, et al. Zinc supplementation enhances hepatic regeneration by preserving hepatocyte nuclear factor-4 alpha in mice subjected to long-term ethanol administration. Am J Pathol 2008; 172:916–925.

Kato N, Tamura G, Motoyama T. Hypomethylation of hepatocyte nuclear factor-1beta (HNF-1beta) CpG island in clear cell carcinoma of the ovary. Virchows Arch 2008; 452:175–180.

Lee HJ, Hwang M, Chattopadhyay S, Choi HS, et al. Hepatocyte nuclear factor-3 alpha (HNF-3 alpha) negatively regulates androgen receptor transactivation in prostate cancer cells. Biochem Biophys Res Commun 2008; 367:481–486.

Liu FJ, Song X, Yang D, Deng R, et al. The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4 alpha. Biochem J 2008; 409:243–250.

Lu P, Rha GB, Chi YI. Structural basis of disease-causing mutations in hepatocyte nuclear factor 1 beta. Biochemistry 2007; 46:12071–12080.

Onica T, Nichols K, Larin M, Ng L, et al. Dexamethasone-mediated up-regulation of human CYP2A6 involves the glucocorticoid receptor and increased binding of hepatic nuclear factor 4 alpha to the proximal promoter. Mol Pharmacol 2008; 73:451–460.

Schafer G, Wissmann C, Hertel J, Lunyak V, et al. Regulation of vascular endothelial growth factor D by orphan receptors hepatocyte nuclear factor-4 alpha and chicken ovalbumin upstream promoter transcription factors 1 and 2. Cancer Res 2008; 68:457–466.

Back to Top | Article Outline

Molecular biology methods and data analysis tools

Galperin MY. The molecular biology database collection: 2008 update. Nucleic Acids Res 2008; 36:D2–D4.

Kusano T, Aoki T, Yasuda D, Matsumoto S, et al. Microencapsule technique protects hepatocytes from cryoinjury. Hepatology Res 2008; 38:593–600.

Leanza SM, Burk RD, Rohan TE. Whole genome amplification of DNA extracted from hair samples: Potential for use in molecular epidemiologic studies. Cancer Detect Prev 2007; 31:480–488.

Li MY, Li C, Guan W. Evaluation of coverage variation of SNP chips for genome-wide association studies. Eur J Human Genet 2008; 16:635–643.

Molecular biology technique Q&As - How can I avoid point mutations in PCR? Biotechniques 2008; 44:185.

Molecular biology technique Q&As - How can I avoid point mutations in PCR? Biotechniques 2008; 44:187.

Molecular biology techniques Q&As - stripping antibodies to re-use western blot membranes. Biotechniques 2008; 44:33.

Molecular biology techniques Q&As - Stripping antibodies to re-use western blot membranes. Biotechniques 2008; 44:33.

Nadell CD, Xavier JB, Levin SA, Foster KR. The evolution of quorum sensing in bacterial biofilms - art. no. e14. PLoS Biol 2008; 6:171–179.

Nazmul-Hossain ANM, Patel KJ, Rhodus NL, Moser KL. Microarrays: applications in dental research [Review]. Oral Dis 2008; 14:25–29.

Ny Kristensen N, Olsen J, Gad M, Claesson MH. Genome-wide expression profiling during protection from colitis by regulatory T cells. Inflamm Bowel Dis 2008; 14:75–87.

Sivaraman K, Seshasayee A, Tarwater PM, Cole AM. Codon choice in genes depends on flanking sequence information - implications for theoretical reverse translation - art. no. e16. Nucleic Acids Res 2008; 36:E16.

Back to Top | Article Outline

Lipid metabolism

Davidson M, Meyer PM, Haffner S, Feinstein S, et al. Increased high-density lipoprotein cholesterol predicts the pioglitazone-mediated reduction of carotid intima-media thickness progression in patients with type 2 diabetes mellitus. Circulation 2008; 117:2123–2130.

Grallert H, Sedlmeier EM, Huth C, Kolz M, et al. APOA5 variants and metabolic syndrome in Caucasians. J Lipid Res 2007; 48:2614–2621.

Ilveskoski E, Lehtimaki T, Laaksonen R, Janatuinen T, et al. Improvement of myocardial blood flow by lipid-lowering therapy with pravastatin is modulated by apolipoprotein E genotype. Scand J Clin Lab Invest 2007; 67:723–734.

Jia XM, Ebine NY, Dernonty I, Wang Y, et al. Hypocholesterolaemic effects of plant sterol analogues are independent of ABCG5 and ABCG8 transporter expressions in hamsters. Br J Nutr 2007; 98:550–555.

Li JG, Nanayakkara A, Jun J, Savransky V, et al. Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia. Physiological Genomics 2007; 31:273–280.

Lichtenstein L, Berbee JFP, van Dijk SJ, van Dijk KW, et al. Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-Dependent hepatic cholesterol uptake. Arterioscler Thromb Vasc Biol 2007; 27.

Lopez-Miranda J, Williams C, Lairon D. Dietary, physiological, genetic and pathological influences on postprandial lipid metabolism [Review]. Br J Nutr 2007; 98:458–473.

Lopez D, Socarras JFA, Bedi M, Ness GC. Activation of the hepatic LDL receptor promoter by thyroid hormone. Biochim Biophys Acta Mol Cell Biol Lipids 2007; 1771:1216–1225.

Macut D, Panidis D, Glisic B, Spanos N, et al. Lipid and lipoprotein profile in women with polycystic ovary syndrome. Can J Physiol Pharmacol 2008; 86:199–204.

Mbikay M, Mayne J, Seidah NG, Chretien M. Of PCSK9, cholesterol homeostasis and parasitic infections: Possible survival benefits of loss-offunction PCSK9 genetic polymorphisms. Med Hypotheses 2007; 69:1010–1017.

Rodrigues AC, Hirata MH, Hirata RD. The genetic determinants of atorvastatin response [Review]. Curr Opin Mol Ther 2007; 9:545–553.

Sanchez-Vera I, Bonet B, Viana M, Quintanar A, et al. Changes in plasma lipids and increased low-density lipoprotein susceptibility to oxidation in pregnancies complicated by gestational diabetes: consequences of obesity. Metab-Clin Exp 2007; 56:1527–1533, 2007 Nov.

Sandhu MS, Waterworth DM, Debenham SL, Wheeler E, et al. LDL-cholesterol concentrations: a genome-wide association study. Lancet 2008; 371:483–491.

Santosa S, Demonty I, Lichtenstein AH, Ordovas JM, et al. Single nucleotide polymorphisms in ABCG5 and ABCG8 are associated with changes in cholesterol metabolism during weight loss. J Lipid Res 2007; 48:2607–2613.

Sherva R, Yue P, Schonfeld G, Neuman RJ. Evidence for a quantitative trait locus affecting low levels of apolipoprotein B and low density lipoprotein on chromosome 10 in Caucasian families. J Lipid Res 2007; 48:2632–2639.

Simonen P, Gylling H, Miettinen TA. The validity of serum squalene and non-cholesterol sterols as surrogate markers of cholesterol synthesis and absorption in type 2 diabetes. Atherosclerosis 2008; 197:883–888.

Varret M, Abifadel M, Rabes JP, Boileau C. Genetic heterogeneity of autosomal dominant hypercholesterolemia [Review]. Clin Genet 2008; 73:1–13.

Yoshida T, Yajima K, Hibino T, Kato K, et al. Association of gene polymorphisms with myocardial infarction in individuals with different lipid profiles. Int J Mol Med 2007; 20:581–590.

Back to Top | Article Outline

Genetics of cancer: genome-wide association studies. risk factors and molecular pathways

Ambrosone CB. The promise and limitations of genome-wide association studies to elucidate the causes of breast cancer - art. no. 114. Breast Cancer Research 2007; 9:114.

Demicheli R, Retsky MW, Hrushesky WJM, Baum M, et al. Racial disparities in breast cancer outcome - Insights into host-tumor interactions [Review]. Cancer 2007; 110:1880–1888.

Duggan D, Zheng SL, Knowlton M, Benitez D, et al. Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB21P. J Natl Cancer Inst 2007; 99:1836–1844.

Hu LF, Qiu QH, Fu SM, Sun D, et al. A genome-wide scan suggests a susceptibility locus on 5p13 for nasopharyngeal carcinoma. Eur J Human Genet 2008; 16:343–349.

Lu XS, Lu X, Wang ZCG, Iglehart JD, et al. Predicting features of breast cancer with gene expression patterns. Breast Cancer Res Treat 2008; 108:191–201.

Nevins JR. New breast cancer genes - Discovery at the intersection of complex data sets. Cancer Cell 2007; 12:497–499.

Back to Top | Article Outline

Obesity and dyslipidemia: genetics and pathology

Andersen G, Burgdorf KS, Sparso T, Borch-Johnsen K, et al. AHSG tag single nucleotide Polymorphisms associate with type 2 diabetes and dyslipidemia: Studies of metabolic traits in 7,683 white danish subjects. Diabetes 2008; 57:1427–1432.

Dahlin LB, Thrainsdottir S, Cederlund R, Thomsen NOB, et al. Vibrotactile sense in median and ulnar nerve innervated fingers of men with Type 2 diabetes, normal or impaired glucose tolerance. Diabet Med 2008; 25:543–549.

Dedoussis GV. Apolipoprotein polymorphisms and familial hypercholesterolemia [Review]. Pharmacogenomics 2007; 8:1179–1189.

Evans D, Beil FU. The D9N, N291S and S447X variants in the lipoprotein lipase (LPL) gene are not associated with Type III Hyperlipidemia - art. no. 56. BMC Medical Genetics 2007:56.

Farnier M. Dyslipidemia and abdominal obesity: mechanisms and characteristics (Part I) [Review] [French]. Arch Mal Coeur Vaiss 2007; 100:979–984.

Farnier M. Dyslipidemia and abdominal obesity: therapeutic approaches (Part II) [Review] [French]. Arch Mal Coeur Vaiss 2007; 100:985–.

Farooqi S. Insights from the genetics of severe childhood obesity. Horm Res 2007; 68:5–7.

Guisasola FA, Mavros P, Nocea G, Alemao E, et al. Glycaemic control among patients with type 2 diabetes mellitus in seven European countries: findings from the Real-Life Effectiveness and Care Patterns of Diabetes Management (RECAP-DM) study. Diabetes Obes Metab 2008; 10.

Hansen MK, Connolly TM. Nuclear receptors as drug targets in obesity, dyslipidemia and atherosclerosis [Review]. Curr Opin Investig Drugs 2008; 9:247–255.

Heinonen SE, Leppanen P, Kholova I, Lumivuori H, et al. Increased atherosclerotic lesion calcification in a novel mouse model combining insulin resistance, hyperglycemia, and Hypercholesterolemia. Circ Res 2007; 101:1058–1067.

Homsma SJM, Huijgen R, Middeldorp S, Sijbrands EJG, et al. Molecular screening for familial hypercholesterolaemia: consequences for life and disability insurance. Eur J Human Genet 2008; 16:14–17.

Huertas-Vazquez A, Plaisier C, Weissglas-Volkov D, Sinsheimer J, et al. TCF7L2 is associated with high serum triacylglycerol and differentially expressed in adipose tissue in families with familial combined hyperlipidaemia. Diabetologia 2008; 51:62–69.

Iughetti L, Predieri B, Balli F, Calandra S. Rational approach to the treatment for heterozygous familial hypercholesterolemia in childhood and adolescence: A review [Review]. J Endocrinol Invest 2007; 30:700–719.

Koonen DPY, Jacobs RL, Febbraio M, Young ME, et al. Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity. Diabetes 2007; 56:2863–2871.

Kotani K, Shimohiro H, Adachi S, Sakane N. Non-high-density lipoprotein cholesterol levels and recent involuntary weight gain among asymptomatic female subjects. Clin Chem Lab Med 2008; 46:541–544.

Liu J, Sun HB, Wang XF, Mu DY, et al. Effects of oleanolic acid and maslinic acid on hyperlipidemia. Drug Dev Res 2007; 68:261–266.

Lupi R, Mancarella R, Del Guerra S, Bugliani M, et al. Effects of exendin-4 on islets from type 2 diabetes patients. Diabetes Obes Metab 2008; 10.

Ma KL, Ruan XZ, Powis SH, Chen Y, et al. Sirolimus modifies cholesterol Homeostasis in hepatic cells: A potential molecular mechanism for Sirolimus-Associated Dyslipidemia. Transplantation 2007; 84:1029–1036.

Martinez-Hernandez A, Enriquez L, Moreno-Moreno MJ, Marti A. Genetics of obesity. Public Health Nutr 2007; 10:1138–1144.

Mori Y, Hirano T, Nagashima M, Shiraishi Y, et al. Decreased peroxisome proliferator-activated receptor a gene expression is associated with dyslipidemia in a rat model of chronic renal failure. Metab-Clin Exp 2007; 56:1714–1718, 2007 Dec.

Okada K, Yano M, Doki Y, Azama T, et al. Injection of LPS causes transient suppression of biological clock genes in rats. J Surg Res 2008; 145:5–12.

Quagliarini F, Vallve JC, Campagna F, Alvaro A, et al. Autosomal recessive hypercholesterolemia in Spanish kindred due to a large deletion in the ARH gene. Mol Genet Metab 2007; 92:243–248.

Sanchez-Vera I, Bonet B, Viana M, Quintanar A, et al. Changes in plasma lipids and increased low-density lipoprotein susceptibility to oxidation in pregnancies complicated by gestational diabetes: consequences of obesity. Metab-Clin Exp 2007; 56:1527–1533, 2007 Nov.

Scott AL, Humphries KH, Frohlich JJ, Birmingham L. Appropriateness of current thresholds for obesity-related measures among Aboriginal people. Can Med Assoc J 2007; 177:1499–1505, 2007 Dec 4.

Smith AJP, Ahmed F, Nair D, Whittall R, et al. A functional mutation in the LDLR promoter (-139C > G) in a patient with familial hypercholesterolemia. Eur J Human Genet 2007; 15:1186–1189.

Sniderman A, Bailey SD, Engert JC. Familial combined hyperlipidaemia: how can genetic disorders be common, complex and comprehensible? Clin Sci (Colch) 2007; 113:365–367.

Vexiau P, Mavros P, Krishnarajah G, Lyu R, et al. Hypoglycaemia in patients with type 2 diabetes treated with a combination of metformin and sulphonylurea therapy in France. Diabetes Obes Metab 2008; 10.

Vongsuvanh R, Hooper AJ, Coakley JC, Macdessi JS, et al. Novel mutations in abetalipoproteinaemia and homozygous familial hypobetalipoproteinaemia. J Inherit Metab Dis 2007; 30:990.

Wohl D, Scherzer R, Heymsfzeld S, Simberkoff M, et al. The associations of regional adipose tissue with lipid and lipoprotein levels in HIV-infected men. JAIDS 2008; 48:44–52.

Xie L, Gong QH, Xie ZG, Liang ZM, et al. Two novel mutations of the LDL receptor gene associated with familial hypercholesterolemia in a Chinese family. Chin Med J 2007; 120:1694–1699.

Yamada Y, Matsuo H, Warita S, Watanabe S, et al. Prediction of genetic risk for dyslipidemia. Genomics 2007; 90:551–558.

Yang KC, Su YN, Shew JY, Yang KY, et al. LDLR and ApoB are major genetic causes of autosomal dominant hypercholesterolemia in a Taiwanese population. J Formos Med Assoc 2007; 106:799–807.

Back to Top | Article Outline

Mitochondrial genetics

Ahmad S, Ghosh A, Nair DL, Seshadri M. Simultaneous extraction of nuclear and mitochondrial DNA from human blood. Genes Genet Syst 2007; 82:429–432.

Andres O, Ronn AC, Bonhomme M, Keller-Mann T, et al. A microarray system for Y chromosomal and mitochondrial single nucleotide polymorphism analysis in chimpanzee populations. Mol Ecol Resour 2008; 8:529–539.

Angella AF, Gil LHS, da Silva LHP, Ribolla PEM. Population structure of the malaria vector Anopheles darlingi in Rondonia, Brazilian Amazon, based on mitochondrial DNA. Mem Inst Oswaldo Cruz 2007; 102:953–958.

Ashton GV, Stevens MI, Hart MC, Green DH, et al. Mitochondrial DNA reveals multiple Northern Hemisphere introductions of Caprella mutica (Crustacea, Amphipoda). Mol Ecol 2008; 17:1293–1303.

Atkinson QD, Gray RD, Drummond AJ. MtDNA variation predicts population size in humans and reveals a major southern Asian chapter in human prehistory. Mol Biol Evol 2008; 25:468–474.

Attwood SW, Fatih FA, Mondal MMH, Alim MA, et al. A DNA sequence-based study of the Schistosoma indicum (Trematoda: Digenea) group: population phylogeny, taxonomy and historical biogeography. Parasitology 2007; 134:2009–2020.

Baloh RH. Mitochondrial dynamics and peripheral neuropathy. Neuroscientist 2008; 14:12–18.

Bandelt HJ, Parson W. Consistent treatment of length variants in the human mtDNA control region: a reappraisal. Int J Legal Med 2008; 122:11–21.

Benn M, Schwartz M, Nordestgaard BG, Tybjaerg-Hansen A. Mitochondrial haplogroups - Ischemic cardiovascular disease, other diseases, mortality, and longevity in the general population. Circulation 2008; 117:2492–2501.

Bielinski SJ, Pankow JS, Boerwinkle E, Bray MS, et al. Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study. Acta Diabetol 2008; 45:179–182.

Bigg GR, Cunningham CW, Ottersen G, Pogson GH, et al. Ice-age survival of Atlantic cod: agreement between palaeoecology models and genetics. Philos Trans R Soc B-Biol Sci 2008; 275:163–NIL_13, 2008 Jan 22.

Blakeslee AMH, Byers JE, Lesser MP. Solving cryptogenic histories using host and parasite molecular genetics: the resolution of Littorina littorea's North American origin. Mol Ecol 2008; 17:3684–3696.

Boissin E, Feral JP, Chenuil A. Defining reproductively isolated units in a cryptic and syntopic species complex using mitochondrial and nuclear markers: the brooding brittle star, Amphipholis squamata (Ophiuroidea). Mol Ecol 2008; 17:1732–1744.

Boles RG, Gardner A. Sex ratios and mitochondrial genetics in migraine. Cephalalgia 2008; 28:1001–1002.

Bos DH, Gopurenko D, Williams RN, De Woody JA. Inferring population history and demography using microsatellites, mitochondrial DNA, and major histocompatibility complex (MHC) genes. Evolution 2008; 62:1458–1468.

Bowen BW, Karl SA. Population genetics and phylogeography of sea turtles [Review]. Mol Ecol 2007; 16:4886–4907.

Brown JE, Stepien CA. Ancient divisions, recent expansions: phylogeography and population genetics of the round goby Apollonia melanostoma. Mol Ecol 2008; 17:2598–2615.

Burger G, Lavrov DV, Forget L, Lang BF. Sequencing complete mitochondrial and plastid genomes. Nat Protoc 2007; 2:603–614.

Burke RE. Programmed cell death and new discoveries in the genetics of parkinsonism [Review]. J Neurochem 2008; 104:875–890.

Capri M, Salvioll S, Monti D, Caruso C, et al. Human longevity within an evolutionary perspective: The peculiar paradigm of a post-reproductive genetics [Review]. Exp Gerontol 2008; 43:53–60.

Castro ALF, Stewart BS, Wilson SG, Hueter RE, et al. Population genetic structure of Earth's largest fish, the whale shark (Rhincodon typus). Mol Ecol 2007; 16:5183–5192.

Chae JH, Lee JS, Kim KJ, Hwang YS, et al. Biochemical and genetic analysis of Leigh syndrome patients in Korea. Brain Dev 2008; 30:387–390.

Cookson MR, Dauer W, Dawson T, Fon EA, et al. The roles of kinases in familial Parkinson's disease. J Neurosci 2007; 27:11865–11868.

Cooper MA, Adam RD, Worobey M, Sterling CR. Population genetics provides evidence for recombination in Giardia. Curr Biol 2007; 17:1984–1988.

Cortes-Rodriguez N, Hernandez-Banos BE, Navarro-Siguenza AG, Peterson AT, et al. Phylogeography and population genetics of the Amethyst-throated Hummingbird (Lampornis amethystinus). Molecular Phylogenetics and Evolution 2008; 48:1–11.

Crimi M, Rigolio R. The mitochondrial genome, a growing interest inside an organelle [Review]. Int J Nanomed 2008; 3:51–57.

Deshpande AM, Wong DT. Molecular mechanisms of head and neck cancer [Review]. Expert Rev Anticancer Ther 2008; 8:799–809.

Elderkin CL, Christian AD, Metcalfe-Smith JL, Berg DJ. Population genetics and phylogeography of freshwater mussels in North America, Elliptio dilatata and Actinonaias ligamentina (Bivalvia: Unionidae). Mol Ecol 2008; 17:2149–2163.

Faure B, Bierne N, Tanguy A, Bonhomme F, et al. Evidence for a slightly deleterious effect of intron polymorphisms at the EF1 alpha gene in the deep-sea hydrothermal vent bivalve Bathymodiolus. Gene 2007; 406:99–107.

Feldmann G, Maitra A. Molecular genetics of pancreatic ductal adenocarcinomas and recent implications for translational efforts [Review]. J Molecular Diagnostics 2008; 10:111–122.

Fernandez O, Fernandez V, Martinez-Cabrera V, Mayorga C, et al. Multiple sclerosis in Gypsies from southern Spain: prevalence, mitochondrial DNA haplogroups and HLA class II association. Tissue Antigens 2008; 71:426–433.

Ficetola GF, Bonin A, Miaud C. Population genetics reveals origin and number of founders in a biological invasion. Mol Ecol 2008; 17:773–782.

Gasser T. Update on the genetics of Parkinson's disease. Mov Disord 2007; 22:S343–S350.

Good JM, Hird S, Reid N, Demboski JR, et al. Ancient hybridization and mitochondrial capture between two species of chipmunks. Mol Ecol 2008; 17:1313–1327.

Hammer SE, Schwammer HM, Suchentrunk F. Evidence for introgressive hybridization of captive markhor (Capra falconeri) with domestic goat: Cautions for reintroduction. Biochem Genet 2008; 46:216–226.

Haque ME, Grasso D, Miller C, Spremulli LL, et al. The effect of mutated mitochondrial ribosomal proteins S16 and S22 on the assembly of the small and large ribosomal subunits in human mitochondria. Mitochondrion 2008; 8:254–261.

Higashimoto T, Baldwin EE, Gold JI, Boles RG. Reflex sympathetic dystrophy: complex regional pain syndrome type I in children with mitochondrial disease and maternal inheritance. Arch Dis Child 2008; 93:390–397.

Hong MY, Lee EM, Jo YH, Park HC, et al. Complete nucleotide sequence and organization of the mitogenome of the silk moth Caligula boisduvalii (Lepidoptera: Saturniidae) and comparison with other lepidopteran insects. Gene 2008; 413:49–57.

Hu M, Jex AR, Campbell BE, Gasser RB. Long PCR amplification of the entire mitochondrial genome from individual helminths for direct sequencing. Nat Protoc 2007; 2:2339–2344.

Hu YC, Zhang Q, Rao GY, Sodmergen n. Occurrence of plastids in the sperm cells of Caprifoliaceae: Biparental plastid inheritance in angiosperms is unilaterally derived from maternal inheritance. Plant Cell Physiol 2008; 49:958–968.

Imarisio S, Carmichael J, Korolchuk V, Chen CW, et al. Huntington's disease: from pathology and genetics to potential therapies [Review]. Biochem J 2008; 412:191–209.

Jalil MF, Cable J, Inyor JS, Lackman-Ancrenaz I, et al. Riverine effects on mitochondrial structure of Bornean orang-utans (Pongo pygmaeus) at two spatial scales. Mol Ecol 2008; 17:2898–2909.

Johnson SE, Lei R, Martin SK, Irwin MT, et al. Does Eulemur cinereiceps exist? Preliminary evidence from genetics and ground surveys in southeastern Madagascar. Am J Primatol 2008; 70:372–385.

Katrangi E, D'Souza G, Boddapati SV, Kulawiec M, et al. Xenogenic transfer of isolated murine mitochondria into human rho(0) cells can improve respiratory function. Rejuv Res 2007; 10:561–570.

Kawakami T, Butlin RK, Adams M, Saint KM, et al. Differential gene flow of mitochondrial and nuclear DNA markers among chromosomal races of Australian morabine grasshoppers (Vandiemenella, viatica species group). Mol Ecol 2007; 16:5044–5056.

Kim H, Lee S. Molecular systematics of the genus Megoura (Hemiptera: Aphididae) using mitochondrial and nuclear DNA sequences. Mol Cells 2008; 25:510–522.

Kirkwood TBL. Understanding ageing from an evolutionary perspective. J Intern Med 2008; 263:117–127.

Klein J, Sato A, Nikolaidis N. MHC, TSP, and the origin of species: From immunogenetics to evolutionary genetics [Review]. Annu Rev Genet 2007:281–304.

Kotlik P, Markova S, Choleva L, Bogutskaya NG, et al. Divergence with gene flow between Ponto-Caspian refugia in an anadromous cyprinid Rutilus frisii revealed by multiple gene phylogeography. Mol Ecol 2008; 17:1076–1088.

Kronforst MR, Gilbert LE. The population genetics of mimetic diversity in Heliconius butterflies. Philos Trans R Soc B-Biol Sci 2008; 275:493–500, 2008 Mar 7.

Kuhn K, Streit B, Schwenk K. Conservation of structural elements in the mitochondrial control region of Daphnia. Gene 2008; 420:107–112.

Kunej T, Wang Z, Michal JJ, Daniels TF, et al. Functional UQCRC1 polymorphisms affect promoter activity and body lipid accumulation. Obesity 2007; 15:2896–2901.

Leschen RAB, Buckley TR, Harman HM, Shulmeister J. Determining the origin and age of the Westland beech (Nothofagus) gap, New Zealand, using fungus beetle genetics. Mol Ecol 2008; 17:1256–1276.

Lev N, Ickowicz D, Melamed E, Offen D. Oxidative insults induce DJ-1 upregulation and redistribution: Implications for neuroprotection. Neurotoxicology 2008; 29:397–405.

Li MW, Lin RQ, Song HQ, Sani RA, et al. Electrophoretic analysis of sequence variability in three mitochondrial DNA regions for ascaridoid parasites of human and animal health significance. Electrophoresis 2008; 29:2912–2917.

Lind CE, Evans BS, Taylor JJU, Jerry DR. Population genetics of a marine bivalve, Pinctada maxima, throughout the Indo-Australian Archipelago shows differentiation and decreased diversity at range limits. Mol Ecol 2007; 16:5193–5203.

Lindemeyer RG, Goldberg E, Pinto A. Dental management of a child with congenital Sideroblastic anemia: A case report. Pediatr Dent 2007; 29:315–319.

Lister R, Carrie C, Duncan O, Ho LHM, et al. Functional definition of outer membrane proteins involved in preprotein import into mitochondria. Plant Cell 2007; 19:3739–3759.

Long SJ, Jirku M, Mach J, Ginger ML, et al. Ancestral roles of eukaryotic frataxin: mitochondrial frataxin function and heterologous expression of hydrogenosomal Trichomonas homologues in trypanosomes. Mol Microbiol 2008; 69:94–109.

Low NC. Sex ratios and mitochondrial genetics in migraine - Response. Cephalalgia 2008; 28:1002.

Luttikhuizen PC, Campos J, van Bleijswijk J, Peijnenburg KTCA, et al. Phylogeography of the common shrimp, Crangon crangon (L.) across its distribution range [Review]. Molecular Phylogenetics and Evolution 2008; 46:1015–1030.

Malyarchuk B, Grzybowski T, Derenko M, Perkova M, et al. Mitochondrial DNA phylogeny in eastern and western Slavs. Mol Biol Evol 2008; 25:1651–1658.

Mancini E, De Biase A, Mariottini P, Bellini A, et al. Structure and evolution of the mitochondrial control region of the pollen beetle Meligethes thalassophilus (Coleoptera: Nitidulidae). Genome 2008; 51:196–207.

Martins J, Solomon SE, Mikheyev AS, Mueller UG, et al. Nuclear mitochondrial-like sequences in ants: evidence from Atta cephalotes (Formicidae: Attini). Insect Mol Biol 2007; 16:777–784.

McCauley DE, Ellis JR. Recombination and linkage disequilibrium among mitochondrial genes in structured populations of the gynodioecious plant Silene vulgaris. Evolution 2008; 62:823–832.

McCauley DE, Olson MS. Do recent findings in plant mitochondrial molecular and population genetics have implications for the study of gynodioecy and cytonuclear conflict ? [Review]. Evolution 2008; 62:1013–1025.

Melvin RG, Katewa SD, Ballard JWO. A candidate complex approach to study functional mitochondrial DNA changes: Sequence variation and quaternary structure modeling of Drosophila simulans cytochrome c oxidase. J Mol Evol 2008; 66:232–242.

Mittwoch U. Different gene expressions on the left and the right: A genotype/phenotype mismatch in need of attention. Ann Hum Genet 2008; 72:2–9.

Mizuno Y, Hattori N, Kubo SI, Sato S, et al. Progress in the pathogenesis and genetics of Parkinson's disease [Review]. Philos Trans R Soc B-Biol Sci 2008; 363:2215–2227, 2008 Jun 27.

Morgan MJ, Hunter D, Pietsch R, Osborne W, et al. Assessment of genetic diversity in the critically endangered Australian corroboree frogs, Pseudophryne corroboree and Pseudophryne pengilleyi, identifies four evolutionarily significant units for conservation. Mol Ecol 2008; 17:3448–3463.

Morishima K, Nakamura-Shiokawa Y, Bando E, Li YJ, et al. Cryptic clonal lineages and genetic diversity in the loach Misgurnus anguillicaudatus (Teleostei: Cobitidae) inferred from nuclear and mitochondrial DNA analyses. Genetica 2008; 132:159–171.

Munoz J, Gomez A, Green AJ, Figuerola J, et al. Phylogeography and local endemism of the native Mediterranean brine shrimp Artemia salina (Branchiopoda: Anostraca). Mol Ecol 2008; 17:3160–3177.

Murphy R, Ellard S, Hattersley AT. Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes [Review]. Nat Clin Pract Endocrinol Metabol 2008; 4:200–213.

Nabholz B, Glemin S, Galtier N. Strong variations of mitochondrial mutation rate across mammals - the longevity hypothesis. Mol Biol Evol 2008; 25:120–130.

Ort BS, Pogson GH. Molecular population genetics of the male and female mitochondrial DNA molecules of the california sea mussel, Mytilus californianus. Genetics 2007; 177:1087–1099.

Paneto GG, Martins JA, Longo LVG, Pereira GA, et al. Heteroplasmy in hair: Differences among hair and blood from the same individuals are still a matter of debate. Forensic Sci Int 2007; 173:117–121.

Pankratz N, Foroud T. Genetics of Parkinson disease [Review]. Genet Med 2007; 9:801–811.

Pavlova A, Zink RM, Drovetski SV, Rohwer S. Pleistocene evolution of closely related sand martins Riparia riparia and R-diluta. Molecular Phylogenetics and Evolution 2008; 48:61–73.

Pedro PM, Sallum MA, Butlin RK. Forest-obligate Sabethes mosquitoes suggest palaeoecological perturbations. Heredity 2008; 101:186–195.

Pereira C, Camougrand N, Manon S, Sousa MJ, et al. ADP/ATP carrier is required for mitochondrial permeabilization and cytochrome c release in yeast apoptosis. Mol Microbiol 2007; 66:571–582.

Plantard O, Picard D, Valette S, Scurrah M, et al. Origin and genetic diversity of Western European populations of the potato cyst nematode (Globodera pallida) inferred from mitochondrial sequences and microsatellite loci. Mol Ecol 2008; 17:2208–2218.

Price DK, Muir C. Conservation implications of hybridization in Hawaiian picture-winged Drosophila [Review]. Molecular Phylogenetics and Evolution 2008; 47:1217–1226.

Rach J, De Salle R, Sarkar IN, Schierwater B, et al. Character-based DNA barcoding allows discrimination of genera, species and populations in Odonata. Philos Trans R Soc B-Biol Sci 2008; 275:237–247, 2008 Feb 7.

Reinders J, Wagner K, Zahedi RP, Stojanovski D, et al. Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 2007; 6:1896–1906.

Ricaut FX, Thomas T, Arganini C, Staughton J, et al. Ethnologue: Languages of the world [Review]. Ann Hum Genet 2008; 72:349–367.

Rodriguez-Robles JA, Jezkova T, Leal M. Genetic structuring in the threatened “Lagartijo del Bosque Seco” (Anolis cooki) from Puerto Rico. Molecular Phylogenetics and Evolution 2008; 46:503–514.

Roy M, Dubois MP, Proffit M, Vincenot L, et al. Evidence from population genetics that the ectomycorrhizal basidiomycete Laccaria amethystina is an actual multihost symbiont. Mol Ecol 2008; 17:2825–2838.

Sacconi S, Salviati L, Nishigaki Y, Walker WF, et al. A functionally dominant mitochondrial DNA mutation. Hum Mol Genet 2008; 17:1814–1820.

Salas A, Jaime JC, Alvarez-Iglesias V, Carracedo A. Gender bias in the multiethnic genetic composition of central Argentina. J Hum Genet 2008; 53:662–674.

Santos MH, Lopes IF, Del Lama SN. Population genetic study of mitochondrial DNA in Roseate spoonbill (Aves; Platalea ajaja) breeding colonies from the Pantanal wetlands, Brazil. Biochem Genet 2008; 46:492–505.

Scarpassa VM, Cardoza TB, Cardoso RP. Population genetics and phylogeography of Aedes aegipti (Diptera: Culicidae) from Brazil. Am J Trop Med Hyg 2008; 78:895–903.

Shoo LP, Rose R, Doughty P, Austin JJ, et al. Diversification patterns of pebble-mimic dragons are consistent with historical disruption of important habitat corridors in and Australia. Molecular Phylogenetics and Evolution 2008; 48:528–542.

Tafanelli L, Avierinos JF, Thuny F, Pelissier JF, et al. Mitochondrial cardiomyopathy in an adult: a case history [French]. Arch Mal Coeur Vaiss 2007; 100:1021–1024.

Takeda H. Draft genome of the medaka fish: A comprehensive resource for medaka developmental genetics and vertebrate evolutionary biology [Review]. Dev Growth Differ 2008; 50:S157–S166.

Tomozawa M, Suzuki H. A trend of central versus peripheral structuring in mitochondrial and nuclear gene sequences of the Japanese wood mouse, Apodemus speciosus. Zool Sci 2008; 25:273–285.

Turner LM, Hoekstra HE. Reproductive protein evolution within and between species: maintenance of divergent ZP3 alleles in Peromyscus. Mol Ecol 2008; 17:2616–2628.

Tzika AC, Koenig S, Miller R, Garcia G, et al. Population structure of an endemic vulnerable species, the Jamaican boa (Epicrates subflavus). Mol Ecol 2008; 17:533–544.

Ujvari B, Dowton M, Madsen T. Population genetic structure, gene flow and sex-biased dispersal in frillneck lizards (Chlamydosaurus kingii). Mol Ecol 2008; 17:3557–3564.

Underhill PA, Kivisild T. Use of Y chromosome and mitochondrial DNA population structure in tracing human migrations [Review]. Annu Rev Genet 2007:539–564.

Valdiosera CE, Garcia-Garitagoitia JL, Garcia N, Doadrio I, et al. Surprising migration and population size dynamics in ancient Iberian brown bears (Ursus arctos). Proc Natl Acad Sci USA 2008; 105:5123–5128.

Valdiosera CE, Garcia N, Anderung C, Dalen L, et al. Staying out in the cold: glacial refugia and mitochondrial DNA phylogeography in ancient European brown bears. Mol Ecol 2007; 16:5140–5148.

Vaxillaire M, Froguel P. Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes [Review]. Endocr Rev 2008; 29:254–264.

Velez-Zuazo X, Ramos WD, van Dam RP, Diez CE, et al. Dispersal, recruitment and migratory behaviour in a hawksbill sea turtle aggregation. Mol Ecol 2008; 17:839–853.

Venetis C, Theologidis L, Zouros E, Rodakis GC. A mitochondrial genome with a reversed transmission route in the Mediterranean mussel Mytilus galloprovincialis. Gene 2007; 406:79–90.

Virgilio M, Backeijau T, Barr N, De Meyer M. Molecular evaluation of nominal species in the Ceratitis fasciventris, C-anonae, C-rosa complex (Diptera: Tephritidae). Molecular Phylogenetics and Evolution 2008; 48:270–280.

Wallace DC. Anecdotal, historical and critical commentaries on genetics. Genetics 2008; 179:727–735.

Wayne RK, Ostrander EA. Lessons learned from the dog genome [Review]. Trends Genet 2007; 23:557–567.

Weaver TD, Roseman CC. New developments in the genetic evidence for modern human origins [Review]. Evolutionary Anthropology 2008; 17:69–80.

Whiteman NK, Kimball RT, Parker PG. Co-phylogeography and comparative population genetics of the threatened Galapagos hawk and three ectoparasite species: ecology shapes population histories within parasite communities. Mol Ecol 2007; 16:4759–4773.

Xu H, De Luca SZ, O'Farrell PH. Manipulating the metazoan mitochondrial genome with targeted restriction enzymesu. Science 2008; 321:575–577.

Yadava N, Potluri P, Scheffler IE. Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly. Int J Biochem Cell Biol 2008; 40:447–460.

Zeisset I, Beebee T. Amphibian phylogeography: a model for understanding historical aspects of species distributions [Review]. Heredity 2008; 101:109–119.

Zhang F, Jiang Z, Zeng Y, McCarthy T. Development of primers to characterize the mitochondrial control region of the snow leopard (Uncia uncia). Mol Ecol Notes 2007; 7:1196–1198.

Zoraster RM, Rison RA. Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy. Clin Neurol Neurosurg 2008; 110:627–630.

Zuryn S, Kuang J, Ebert P. Mitochondrial modulation of phosphine toxicity and resistance in Caenorhabditis elegans. Toxicol sci 2008; 102:179–186.

Back to Top | Article Outline

CIDE proteins and metabolic disorders

Review: (pp. 121–126)

Desguerre I, Barnerias C, Valayannopoulos V. Peripheral neuropathy as a presentation of metabolic disorders in childhood [French]. Rev Neurol (Paris) 2007; 163:1256–1259.

Huq MDM, Gupta P, Wei LN. Post-translational modifications of nuclear co-repressor RIP140: A therapeutic target for metabolic diseases [Review]. Current Medicinal Chemistry 2008; 15:386–392.

•• Li JZ, Ye J, Xue B, et al. Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation. Diabetes 2007; 56:2523–2532.[04]

Lorenzo C, Nath SD, Hanley AJG, Abboud HE, et al. Relation of low glomerular filtration rate to metabolic disorders in individuals without diabetes and with normoalbuminuria. Clin J Am Soc Nephrol 2008; 3:783–789.

Nagao K, Yanagita T. Bioactive lipids in metabolic syndrome [Review]. Prog Lipid Res 2008; 47:127–146.

Neves FJ, Bousquet-Santos K, Silva BM, Soares PPS, et al. Preserved heart rate variability in first-degree relatives of subjects with Type 2 diabetes mellitus without metabolic disorders. Diabet Med 2008; 25:355–359.

•• Nishino N, Tamori Y, Tateya S, et al. FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J Clin Invest 2008; 118:2808–2821.[06]

Oliveira AC, Oliveira AM, Adan LF, Oliveira NF, et al. C-reactive protein and metabolic syndrome in youth: A strong relationship? Obesity 2008; 16:1094–1098.

Pan WH, Yeh WT, Weng LC. Epidemiology of metabolic syndrome in Asia. Asia Pac J Clin Nutr 2008; 17:37–42.

Poppitt SD, Keogh GF, Lithander FE, Wang Y, et al. Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-alpha, and C-reactive protein to a high-fat dietary load. Nutrition 2008; 24:322–329.

•• Puri V, Konda S, Ranjit S, et al. Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage. J Biol Chem 2007; 282:34213–34218.[27]

• Puri V, Ranjit S, Konda S, et al. Cidea is associated with lipid droplets and insulin sensitivity in humans. Proc Natl Acad Sci U S A 2008; 105:7833–7838.[25]

•• Qi J, Gong J, Zhao T, et al. Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue. EMBO J 2008; 27:1537–1548.[24]

Sicras-Mainar A, Blanca-Tamayo M, Rejas-Gutierrez J, Navarro-Artieda R. Metabolic syndrome in outpatients receiving antipsychotic therapy in routine clinical practice: A cross-sectional assessment of a primary health care database. Eur Psychiatry 2008; 23:100–108.

Tabara Y, Osawa H, Kawamoto R, Tachibana-Limori R, et al. Reduced high-molecular-weight adiponectin and elevated high-sensitivity C-reactive protein are synergistic risk factors for metabolic syndrome in a large-scale middle-aged to elderly population: The Shimanami health promoting program study. J Clin Endocrinol Metab 2008; 93:715–722.

•• Toh SY, Gong J, Du G, et al. Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice. PLoS ONE 2008; 3:e2890.[05]

Torre-Villalvazo I, Tovar AR, Ramos-Barragan VE, Cerbon-Cervantes MA, et al. Soy protein ameliorates metabolic abnormalities in liver and adipose tissue of rats fed a high fat diet. J Nutr 2008; 138:462–468.

Viollet B, Mounier R, Leclerc J, Yazigi A, et al. Targeting AMP-activated protein kinase as a novel therapeutic approach for the treatment of metabolic disorders [Review]. Diabetes Metab 2007; 33:395–402.

Zhang JH, Sui JJ, Ching CB, Chen WN. Protein profile in neuroblastoma cells incubated with S- and R-enantiomers of ibuprofen by iTRAO-coupled 2-D LC-MS/MS analysis: Possible action of induced proteins on Alzheimer's disease. Proteomics 2008; 8:1595–1607.

Back to Top | Article Outline

Chronobiology, genetics and metabolic syndrome

Review: (pp. 127–134)

Auro K, Kristiansson K, Zethelius B, Berne C, et al. USF1 gene variants contribute to metabolic traits in men in a longitudinal 32-year follow-up study. Diabetologia 2008; 51:464–472.

•• Bray MS, Young ME. Circadian rhythms in the development of obesity: potential role for the circadian clock within the adipocyte. Obes Rev 2007; 8:169–181.[27]

Cardenas J, Frye MA, Marusak SL, Levan der EM, et al. Modal subcomponents of metabolic syndrome in patients with bipolar disorder. J Affect Disord 2008; 106:91–97.

Chuang LM. Human genetics of the metabolic syndrome. Asia Pac J Clin Nutr 2008; 17:43–46.

• Duez H, Staels B. The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism. Diab Vasc Dis Res 2008; 5:82–88.[51]

• Froy O. The relationship between nutrition and circadian rhythms in mammals. Front Neuroendocrinol 2007; 28:61–71.[02]

•• Fuller PM, Lu J, Saper CB. Differential rescue of light- and food-entrainable circadian rhythms. Science 2008; 230:1074–1077.[24]

• García-Prieto MD, Tébar FJ, Nicolás F, et al. Cortisol secretary pattern and glucocorticoid feedback sensitivity in women from a Mediterranean area: relationship with anthropometric characteristics, dietary intake and plasma fatty acid profile. Clin Endocrinol (Oxf) 2007; 66:185–191.[58]

•• Gomez-Abellan P, Hernandez-Morante JJ, Lujan JA, et al. Clock genes are implicated in the human metabolic syndrome. Int J Obesity 2008; 32:121–128.[26]

• Hofstra WA, de Weerd AW. How to assess circadian rhythm in humans: a review of literature. Epilepsy Behav 2008; 13:438–444.[59]

Howard G, Feigin V. Advances in population studies 2007. Stroke 2008; 39:283–285.

•• Laposky AD, Bass J, Kohsaka A, Turek FW. Sleep and circadian rhythms: key components in the regulation of energy metabolism. FEBS Lett 2008; 582:142–151.[03]

• Laposky AD, Bradley MA, Williams DL, et al. Sleep-wake regulation is altered in leptin resistant (db/db) genetically obese and diabetic mice. Am J Physiol Regul Integr Comp Physiol 2008; 295:R2059–R2066.[43]

Lazaros L, Markoula S, Xita N, Giannopoulos S, et al. Association of estrogen receptor-alpha gene polymorphisms with stroke risk in patients with metabolic syndrome. Acta Neurol Scand 2008; 117:186–190.

• Mendoza J, Pevet P, Challet E. High-fat feeding alters the clock synchronization to light. J Physiol 2008; 586:5901–5910.[40]

Pillai SG, Tang Y, van den Oord E, Klotsman M, et al. Factor analysis in the Genetics of Asthma International Network family study identifies five major quantitative asthma phenotypes. Clin Exp Allergy 2008; 38:421–429.

• Prasai MJ, George JT, Scott EM. Molecular clocks, type 2 diabetes and cardiovascular disease. Diab Vasc Dis Res 2008; 5:89–95.[39]

• Ramsey KM, Marcheva B, Kohsaka A, Bass J. The clockwork of metabolism. Annu Rev Nutr 2007; 27:219–240.[49]

Redei EE. Molecular genetics of the stress-responsive adrenocortical axis [Review]. Ann Med 2008; 40:139–148.

• Ruiz Pons M, García Nieto V, García MG, et al. Reduced nocturnal systolic blood pressure dip in obese children. Nefrologia 2008; 28:517–524. Spanish[36]

• Sookoian S, Gemma C, Gianotti TF, et al. Genetic variants of clock transcription factor are associated with individual susceptibility to obesity. Am J Clin Nutr 2008; 87:1606–1615.[54]

• Suwazono Y, Dochi M, Sakata K, et al. A longitudinal study on the effect of shift work on weight gain in male Japanese workers. Obesity 2008; 16:1887–1893.[11]

• Véniant MM, Hale C, Komorowski R, et al. Time of the day for 11beta-HSD1 inhibition plays a role in improving glucose homeostasis in DIO mice. Diabetes Obes Metab 2009; 11:109–117.[63]

•• Van Cauter E, Knutson K. Sleep and the epidemic of obesity in children and adults. Eur J Endocrinol 159(Suppl 1); 2008:S59–S66.[15]

Voruganti VS, Lopez-Alvarenga JC, Nath SD, Rainwater DL, et al. Genetics of variation in HOMA-IR and cardiovascular risk factors in Mexican-Americans. J Mol Med 2008; 86:303–311.

Wierzbicki AS, Graham CA, Young IS, Nicholls DP. Familial combined hyperlipidaemia: Under-defined and under-diagnosed? [Review]. Current Vascular Pharmacology 2008; 6:13–22.

Williams RB. Psychosocial and biobehavioral factors and their interplay in coronary heart disease. Annu Rev Clin Psychol 2008:349–365.

Back to Top | Article Outline

Hypoalphalipoproteinemia in populations of Native American ancestry: an opportunity to assess the interaction of genes and the environment

Review: (pp. 92–97)

• Aulchenko YS, Ripatti S, Lindqvist I, et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 2009; 41:47–55.[53]

Barnholtz-Sloan JS, McEvoy B, Shriver MD, Rebbeck TR. Ancestry estimation and correction for population stratification in molecular epidemiologic association studies. Cancer Epidemiol Biomarkers Prev 2008; 17.

• Barquera S, Hernandez-Barrera L, Tolentino ME, et al. Energy intake from beverages is increasing among Mexican adolescents and adults. J Nutr 2008; 138:2454–2461.[37]

Halder I, Shriver M, Thomas M, Fernandez JR, et al. A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: Utility and applications. Hum Mutat 2008; 29:648–658.

Hughes LB, Morrison D, Kelley JM, Padilla MA, et al. The HLA-DRB1 shared epitope is associated with susceptibility, to rheumatoid arthritis in African Americans through European genetic admixture. Arthritis Rheum 2008; 58:349–358.

• Kathiresan S, Melander O, Guiducci C, et al. Six new loci associated with blood low density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008; 40:189–197.[51]

• Kathiresan S, Willer CJ, Peloso GM, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009; 41:56–65.[52]

• Kooner J, Chambers JC, Aguilar-Salinas CA, et al. Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat Genet 2008; 40:149–151.[49]

• McQueen MJ, Hawken S, Wang X, et al. Lipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control study. Lancet 2008; 372:224–233.[08]

Rangel-Villalobos H, Munoz-Valle JF, Gonzalez-Martin A, Gorostiza A, et al. Genetic admixture, relatedness, and structure patterns among Mexican populations revealed by the Y-chromosome. Am J Phys Anthropol 2008; 135:448–461.

Sankararaman S, Kimmel G, Halperin E, Jordan MI. On the inference of ancestries in admixed populations. Genome Res 2008; 18:668–675.

Sankararaman S, Sridhar S, Kimmel G, Halperin E. Estimating local ancestry in admixed populations. Am J Hum Genet 2008; 82:290–303.

• Schargrodsky H, Hernandez-Hernandez R, Marcet Champagne B, et al. CARMELA: assessment of cardiovascular risk in seven Latin American cities. Am J Med 2008; 121:58–65.[34]

• Stevens G, Dias RH, Kevin JA, et al. Characterizing the epidemiological transition in Mexico: National and subnational burden of diseases, injuries, and risk factors. PLoS Med 5: e125. doi:10.1371/journal.pmed.0050125.[35]

•• Villarreal-Molina MT, Aguilar-Salinas CA, Rodríguez-Cruz M, et al. The ABCA1 R230C variant affects HDL cholesterol levels and body mass index in the Mexican population: association with obesity and obesity-related comorbidities. Diabetes 2007; 56:1881–1887.[60]

• Villarreal-Molina MT, Flores-Dorantes MT, Arellano-Campos O, et al. Association of the ABCA1 R230C variant with early-onset type 2 diabetes in the Mexican population. Diabetes 2008; 57:509–513.[61]

• Willer C, Sanna S, Jackson A, et al. Newly identified loci that influence lipid concentrations and risk of coronary heart disease. Nat Genet 2008; 40:161–169.[50]

Zhang QY, Lewis CE, Wagenknecht LE, Myers RH, et al. Genome-wide admixture mapping for coronary artery calcification in African Americans: The NHLBI family heart study. Genet Epidemiol 2008; 32:264–272.

Back to Top | Article Outline

A network approach to micronutrient genetics: interactions with lipid metabolism

Review: (pp. 112–120)

• Borel P, Moussa M, Reboul E, et al. Human fasting plasma concentrations of vitamin E and carotenoids, and their association with genetic variants in apo C-III, cholesteryl ester transfer protein, hepatic lipase, intestinal fatty acid binding protein and microsomal triacylglycerol transfer protein. Br J Nutr 2008 [Epub ahead of print]. doi:10.1017/S0007114508030754.[45]

• Borel P, Moussa M, Reboul E, et al. Human plasma levels of vitamin E and carotenoids are associated with genetic polymorphisms in genes involved in lipid metabolism. J Nutr 2007; 137:2653–2659.[44]

Brummett BH, Boyle SH, Siegler IC, Zuchner S, et al. Lipid levels are associated with a regulatory polymorphism of the monoamine oxidase-A gene promoter (MAOA-uVNTR). Med Sci Monitor 2008; 14:CR57–CR61.

Burk RF, Hill KE, Nakayama A, Mostert V, et al. Selenium deficiency activates mouse liver Nrf2-ARE but vitamin E deficiency does not. Free Radic Biol Med 2008; 44:1617–1623.

• Curran JE, Jowett JB, Elliott KS, et al. Genetic variation in selenoprotein S influences inflammatory response. Nat Genet 2005; 37:1234–1241.[26]

• Haggarty P. B-vitamins, genotype and disease causality. Proc Nutr Soc 2007; 66:539–547.[05]

• Herbeth B, Gueguen S, Leroy P, et al. The lipoprotein lipase serine 447 stop polymorphism is associated with altered serum carotenoid concentrations in the Stanislas Family Study. J Am Coll Nutr 2007; 26:655–662.[46]

•• Hessel S, Eichinger A, Isken A, et al. CMO1 deficiency abolishes vitamin A production from beta-carotene and alters lipid metabolism in mice. J Biol Chem 2007; 282:33553–33561.[49]

Hubacek JA, Adamkova V, Stavek P, Kubinova R, et al. Apotipoprotein E Arg136 -> Cys mutation and hyperlipidemia in a large central European population sample. Clin Chim Acta 2008; 388:217–218.

Kathiresan S, Musunuru K, Orho-Melander M. Defining the spectrum of alleles that contribute to blood lipid concentrations in humans [Review]. Curr Opin Lipidol 2008; 19:122–127.

Krimbou L, Ruel I, Dastani Z, Alrasadi K, et al. Disorders of high-density lipoprotein biogenesis. Ann Med 2008; 40:39–47.

•• Leung W, Hessel S, Méplan C, et al. Two common single nucleotide polymorphisms in the gene encoding β-carotene 15,15′-monoxygenase alter β-carotene metabolism in female volunteers. FASEB J 2008 [Epub ahead of print] PMID: 19103647.[53]

Massaro D, Massaro GD. Apoe(tm1Unc) mice have impaired alveologenesis, low lung function, and rapid loss of lung function. Am J Physiol-Lung Cell Mol Physiol 2008; 294:L991–L997.

Mehrabian M, Schulthess FT, Nebohacova M, Castellani LW, et al. Identification of ALOX5 as a gene regulating adiposity and pancreatic function. Diabetologia 2008; 51:978–988.

• Meplan C, Crosley LK, Nicol F, et al. Functional effects of a common single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene: interaction with sex. Am J Clin Nutr 2008; 87:1019–1027.[19]

• Meplan C, Crosley LK, Nicol F, et al. Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a gender-specific manner (the SELGEN study). FASEB J 2007; 21:3063–3074.[24]

Moore LE, Pfeiffer RM, Poscablo C, Real FX, et al. Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study. Lancet Oncol 2008; 9:359–366.

Penry JT, Manore MM. Choline: An important micronutrient for maximal endurance-exercise performance? [Review]. Int J Sport Nutr Exerc Metab 2008; 18:191–203.

• Perry JR, Frayling TM. New gene variants alter type 2 diabetes risk predominantly through reduced beta-cell function. Curr Opin Clin Nutr Metab Care 2008; 11:371–377.[33]

• Ravn-Haren G, Olsen A, Tjonneland A, et al. Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study. Carcinogenesis 2006; 27:820–825.[16]

Robert L, Narcy A, Rayssiguier Y, Mazur A, et al. Lipid metabolism and antioxidant status in sucrose vs. potato-fed rats. J Am Coll Nutr 2008; 27:109–116.

Sandhu MS, Waterworth DM, Debenham SL, Wheeler E, et al. LDL-cholesterol concentrations: a genome-wide association study. Lancet 2008; 371:483–491.

Smith JA, Arnett DK, Kelly RJ, Ordovas JM, et al. The genetic architecture of fasting plasma triglyceride response to fenofibrate treatment. Eur J Human Genet 2008; 16:603–613.

• Tabara Y, Osawa H, Kawamoto R, et al. Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening. Diabetes 2008 [Epub ahead of print] PMID: 19033397.[34]

Tokunaga A, Miura A, Okauchi Y, Segawa K, et al. The-1535 promoter variant of the visfatin gene is associated with serum triglyceride and HDL-cholesterol levels in Japanese subjects. Endocr J 2008; 55:205–212.

Willer CJ, Sanna S, Jackson AU, Scuteri A, et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008; 40:161–169.

• Ziouzenkova O, Orasanu G, Sharlach M, et al. Retinaldehyde represses adipogenesis and diet-induced obesity. Nat Med 2007; 13:695–702.[56]

Back to Top | Article Outline

Miscellaneous

Bozina N, Medved V, Kuzman MR, Sain I, et al. Association study of olanzapine-induced weight gain and therapeutic response with SERT gene polymorphisms in female schizophrenic patients. J Psychopharmacol 2007; 21:728–734.

De Moor MHM, Spector TD, Cherkas LF, Falchi M, et al. Genome-wide linkage scan for athlete status in 700 British female DZ twin pairs. Twin Res Hum Genet 2007; 10:812–820, 2007 Dec.

Gallego PH, Shephard N, Bulsara MK, van Bockxmeer FM, et al. Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus. J Diabetes Complications 2008; 22:191–198.

Grosshans H, Filipowicz W. Molecular biology - The expanding world of small RNAs. Nature 2008; 451:414–416.

Jakob T, Kollisch GV, Howaldt M, Bewersdorff M, et al. Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis. J Allergy Clin Immunol 2008; 121:179–184.

Jenkins MM, Rasmussen SA, Moore CA, Honein MA. Ethical issues raised by incorporation of genetics into the National Birth Defects Prevention Study. Am J Med Genet C 2008; 148C:40–46.

Mittwoch U. Different gene expressions on the left and the right: A genotype/phenotype mismatch in need of attention. Ann Hum Genet 2008; 72:2–9.

Robitaille J, Grant AM. The genetics of gestational diabetes mellitus: evidence for relationship with type 2 diabetes mellitus [Review]. Genet Med 2008; 10:240–250.

Smart KA. Brewing yeast genomes and genome-wide expression and proteome profiling during fermentation [Review]. Yeast 2007; 24:993–1013.

Vieira AR, Marazita ML, Goldstein-McHenry T. Genome-wide scan finds suggestive caries loci. J Dent Res 2008; 87:435–439.

Wohl D, Scherzer R, Heymsfzeld S, Simberkoff M, et al. The associations of regional adipose tissue with lipid and lipoprotein levels in HIV-infected men. JAIDS 2008; 48:44–52.

© 2009 Lippincott Williams & Wilkins, Inc.