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Dietary patterns, Mediterranean diet, and cardiovascular disease

Martinez-Gonzalez, Miguel Angela,b; Bes-Rastrollo, Mairaa


In the recent article by Martinez-Gonzalez et al. [1] , a number of errors were introduced by the publisher for which we apologise. Please note the following corrections.

Page 23, left column, middle paragraph, the opening line should read: ‘Two Italian rural male cohorts of the Seven Countries Study (n: 1139) [27 ]’.

Page 23, right column, first paragraph, the opening line should read: ‘The Monitoring Project on Risk Factors and Chronic Diseases in the Netherlands (MORGEN) [29 ]’.

Page 23, right column, third paragraph, the final line should read: ‘was excluded because it was subsequently updated [22 ].’

In Figure 2 the second number on the right x axis should be 2.00, the corrected figure is shown below.

Current Opinion in Lipidology. 25(4):326, August 2014.

doi: 10.1097/MOL.0000000000000044
NUTRITION AND METABOLISM: Edited by Frank M. Sacks and Lawrence J. Appel

Purpose of review The objective of this manuscript was to review the evidence on the association between adherence to a Mediterranean diet (MeDiet) and the risk of cardiovascular disease (CVD). We also updated the results of the last available meta-analysis.

Recent findings In 2013, a landmark study in the field, the PREvención con DIeta MEDiterránea randomized trial, with 7447 high-risk participants, published its final results. They provided a strong support to the beneficial role of a traditional MeDiet for primary cardiovascular prevention. When these results were combined with those of the Lyon Diet Heart Study (a secondary prevention trial), we found that an intervention with a MeDiet was associated with a 38% relative reduction in the risk of CVD clinical events (pooled random-effects risk ratio: 0.62; 95% confidence interval, CI: 0.45–0.85). Regarding observational studies assessing clinical end-points as outcome, we identified seven new cohort studies published after the last meta-analysis. After removing studies that only assessed fatal outcomes, a two-point increase in adherence to the MeDiet (0–9 score) was associated with a significant reduction in cardiovascular events (pooled risk ratio: 0.87; 95% CI: 0.85–0.90) with no evidence of heterogeneity.

Summary Consistent evidence suggests that the promotion of the Mediterranean dietary pattern is an effective and feasible tool for the prevention of CVD.

aDepartment Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain

bCIBERobn, Instituto de Salud Carlos III, Madrid, Spain

Correspondence to Miguel Angel Martinez-Gonzalez, MD, MPH, PhD, Dept. of Preventive Medicine and Public Health, School of Medicine, c/ Irunlarrea, 1 (Ed. Investigación), 31008 Pamplona, Navarra, Spain. Tel: +34 948425600x806463; fax: +34 948425649; e-mail:

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