Increasing evidence suggests that omega 3 fatty acids derived from fish and fish oils may play a protective role in coronary heart disease and its many complications, through a variety of actions, including effects on lipids, blood pressure, cardiac and vascular function, prostanoids, coagulation and immunological responses. Interesting differences between the effects of highly purified eicosapentaenoic acid and docosahexaenoic acid are emerging, which may be relevant in the choice of omega 3 fatty acid for incorporation into food products. On the basis of our current knowledge, we believe it is justified to recommend, particularly to high-risk populations, an increased dietary intake of omega 3 fatty acids through the consumption of fish.
Department of Medicine, University of Western Australia and the West Australian Heart Research Institute (HeartSearch), Perth, Australia
Correspondence to Dr Trevor A. Mori, University Department of Medicine, Box X 2213 GPO, Perth, Western Australia 6847. Tel: +61 8 92240273; fax: +61 8 92240246; e-mail: email@example.com