Article: PDF OnlyPossible mechanisms underlying the cholesterol-raising effect of the coffee diterpene cafestolde Roos, Baukje; Katan, Martijn B. Author Information Division of Human Nutrition and Epidemiology, Wageningen Centre for Food Sciences and the Wageningen Agricultural University. Wageningen. The Netherlands Current Opinion in Lipidology: February 1999 - Volume 10 - Issue 1 - p 41-46 Buy Abstract Cafestol, a coffee diterpene present in unfiltered coffee brews, potently raises serum lipids in humans. The mechanism through which this dietary compound influences lipoprotein metabolism is largely unknown. Unravelling the mechanism of action might lead to new insights into the regulation of serum cholesterol levels in humans. This review summaries ways in which cafestol may act on serum lipids. © 1999 Lippincott Williams & Wilkins, Inc.