CNS INFECTIONS: Edited by Matthijs C. BrouwerEpidemiology of community-acquired bacterial meningitisBrouwer, Matthijs C.; van de Beek, DiederikAuthor Information Department of Neurology, Amsterdam Neuroscience, Academic Medical Centre, Amsterdam, the Netherlands Correspondence to Matthijs C. Brouwer, MD, PhD, Department of Neurology, Centre of Infection and Immunity Amsterdam (CINIMA), Academic Medical Centre, University of Amsterdam, PO Box 22660, 1100DD Amsterdam, the Netherlands. Tel: +31205663842; fax: +31205669374; e-mail: [email protected] Current Opinion in Infectious Diseases: February 2018 - Volume 31 - Issue 1 - p 78-84 doi: 10.1097/QCO.0000000000000417 Buy Metrics Abstract Purpose of review The epidemiology of bacterial meningitis has been dynamic in the past 30 years following introduction of conjugated vaccines against Haemophilus influenzae type B, Streptococcus pneumoniae and Neisseria meningitidis. The purpose of this review is to describe recent developments in bacterial meningitis epidemiology. Recent findings The incidence of bacterial meningitis in Western countries (Finland, Netherlands, and the United States) gradually declined by 3–4% per year to 0.7–0.9 per 100 000 per year in the past 10–20 years. In African countries (Burkina Faso and Malawi), incidence rates are still substantially higher at 10–40 per 100 000 persons per year. Introduction of pneumococcal conjugate vaccines have not consistently decreased overall pneumococcal meningitis incidence because of serotype replacement. Following the introduction of serogroup A and C meningococcal vaccines, the incidence of meningococcal meningitis because of these serogroups strongly decreased. Novel outbreaks in the African meningitis belt by serogroup C and increased incidence of serogroup W in the United Kingdom and the Netherlands were observed recently. Summary Bacterial meningitis remains an important infectious disease, despite a gradual decline in incidence after large-scale vaccination campaigns. Further development of vaccines with broader coverage is important, as is continuous surveillance of bacterial meningitis cases. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.