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Urinary tract infections and bacterial prostatitis in men

Wagenlehner, Florian M.E.a; Weidner, Wolfganga; Pilatz, Adriana; Naber, Kurt G.b

Current Opinion in Infectious Diseases: February 2014 - Volume 27 - Issue 1 - p 97–101
doi: 10.1097/QCO.0000000000000024
URINARY TRACT INFECTIONS: Edited by Suzanne E. Geerlings

Purpose of review The purpose of this review is to highlight advances in research on urinary tract infections (UTIs) and bacterial prostatitis in men in the preceding year.

Recent findings The antiseptic properties of the prostate secretions might be an important factor for prevention of recurrency. Risk factors for UTI in men include prostate enlargement and urological interventions, such as transrectal prostate biopsy. Preventive treatment of prostate enlargement has been demonstrated to reduce frequency of UTI. Ensuing infections after prostate biopsy, such as UTI and bacterial prostatitis, are increasing due to increasing rates of fluoroquinolone resistance. The increasing global antibiotic resistance also significantly affects management of UTI in men, and therefore calls for alternative strategies.

Apart from prevention of complicating factors leading to UTI, a more thorough understanding of the pathophysiology may play a more important role in the future, to define new targets for treatment. Interesting results that might interfere with the intracellular mucosal bacterial load in the bladder wall have been found in the last years.

Summary UTI in men and bacterial prostatitis are currently underrepresented in the medical literature. Increasing antibacterial resistance calls for novel strategies in the prevention and management of UTI and bacterial prostatitis in men.

aClinic of Urology, Pediatric Urology and Andrology, Justus-Liebig-University, Giessen

bTechnical University, Munich, Germany

Correspondence to Professor Dr med Florian M.E. Wagenlehner, Clinic of Urology, Pediatric Urology and Andrology, Justus-Liebig-University, Giessen, Rudolf-Buchheim-Str. 7, D-35385 Giessen, Germany. Tel: +49 641 985 44516; fax: +49 641 985 44509; e-mail:

© 2014 Lippincott Williams & Wilkins, Inc.