Use of crystal methamphetamine, Viagra, and sexual behaviorFisher, Dennis G; Reynolds, Grace L; Napper, Lucy ECurrent Opinion in Infectious Diseases: February 2010 - Volume 23 - Issue 1 - p 53–56 doi: 10.1097/QCO.0b013e328334de0b Sexually transmitted diseases and urinary tract infections Edited: by Anton L. Pozniak Abstract Author Information Purpose of review Methamphetamine (meth) use has been shown in the literature to be associated with high-risk sexual behavior for both homosexual (MSM) and heterosexual samples for over a decade. The use of Viagra has also been shown to be associated with high-risk sexual behavior. The purpose of this review is to update the record on Viagra and on the combination of Viagra and meth use. Recent findings There is now strong evidence that the use of Viagra is associated with HIV seroconversion in MSM. The combination of taking both meth and Viagra is strongly associated with much higher sexually transmitted disease and HIV rates. There is some evidence that Viagra is associated with insertive and meth is associated with receptive anal intercourse by men. Summary The evidence is strong to support the relationship between Viagra use and HIV seroconversion now that more sophisticated analyses have been done. The meth–Viagra recreational drug combination is of very high risk. More research is needed to generate longitudinal and event-level data that are necessary to answer fine-grained questions about drug combinations and the relationship with sexual behavior. California State University, Long Beach, California, USA Correspondence to Professor Dennis G. Fisher, PhD, Center for Behavioral Research and Services, 1090 Atlantic Avenue, Long Beach, CA 90813, USA Tel: +1 562 495 2330 x121; fax: +1 562 983 1421; e-mail: firstname.lastname@example.org © 2010 Lippincott Williams & Wilkins, Inc.