Respiratory infectionsNew recommendations for the treatment of tuberculosisMyers, Joseph P Author Information Department of Internal Medicine, Northeastern Ohio Universities College of Medicine, Akron, Ohio, USA Correspondence to Joseph P. Myers, MD, Summa Health System, 75 Arch Street, Suite 105, Akron, OH 44304, USA Tel: +1 330 375 3894; fax: +1 330 375 3161; e-mail: [email protected] Current Opinion in Infectious Diseases: April 2005 - Volume 18 - Issue 2 - p 133-140 doi: 10.1097/01.qco.0000160902.48942.31 Buy Metrics Abstract Purpose of review The aim of this article is to give practicing physicians a practical approach to the treatment of latent and active tuberculosis and to review newer recommendations and common problems encountered in the treatment of patients with tuberculosis. Recent findings Recently published literature documents the increased incidence of multidrug resistant strains of Mycobacterium tuberculosis, the importance of antituberculosis drug toxicities and drug–drug interactions, persistent problems in the correct interpretation of the tuberculin skin test and ongoing problems with treatment compliance and treatment completion. Summary This article provides a practical approach to the interpretation of the tuberculin skin test, the proper approach to the treatment of latent tuberculosis infection, and a structured approach to the treatment of presumed or documented active tuberculosis infection. Questions about tuberculosis that are often asked of infectious disease and pulmonary specialists are addressed in a very practical manner. © 2005 Lippincott Williams & Wilkins, Inc.