Review ArticleMolecular mechanisms of Salmonella pathogenesisGroisman, Eduardo A.; Mouslim, Chakib Author Information Department of Molecular Microbiology, Howard Hughes Medical Institute, Washington University School of Medicine, St Louis, Missouri, USA Correspondence to Eduardo A. Groisman, Howard Hughes Medical Institute, Washington University School of Medicine, Department of Molecular Microbiology, 660 South Euclid Avenue, Campus Box 8230, St Louis, MO 63110, USA. Tel: +1 314 362 3692; fax: +1 314 747 8228; e-mail: [email protected] Abbreviations NADPH: nicotinamide adenine dinucleotide phosphate, reduced form NSF: N-ethylmaleimide-sensitive fusion protein RNI: reactive nitrogen intermediates ROI: reactive oxygen intermediates SPI: Salmonella pathogenicity island Current Opinion in Infectious Diseases 13(5):p 519-522, October 2000. Buy Abstract The success of a pathogen depends on its capacity to enter a host, circumvent host defense barriers and establish infection. The Gram-negative bacterium Salmonella enterica has evolved different strategies to subvert normal host cellular functions, which allow it to enter into and proliferate within host cells. © 2000 Lippincott Williams & Wilkins, Inc.