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Uptake of biomedical interventions for prevention of sexually transmitted HIV

Abbas, Ume L

Current Opinion in HIV and AIDS: March 2011 - Volume 6 - Issue 2 - p 114–118
doi: 10.1097/COH.0b013e328343ad7e
Epidemic modelling: Edited by Geoffrey Garnett and David P. Wilson

Purpose of the review To examine the population-level effects of introducing and/or expanding biomedical interventions for prevention of human immunodeficiency virus (HIV) sexually transmitted infections through mathematical modeling.

Recent findings Successes of several ground-breaking clinical trials have invigorated the field of HIV prevention with new enthusiasm and opportunities for research into and application of biomedical HIV prevention. Mathematical modeling has advanced in tandem with valuable contributions to both investigative science and public health. New models provide qualitative and quantitative insights regarding the epidemiological impact of the uptake of biomedical interventions, singly and/or in combination including treatment of sexually transmitted infections, condom use, male circumcision, antiretroviral treatment and pre-exposure prophylaxis and vaccine for HIV prevention.

Summary Biomedical interventions are critical for reversing the HIV pandemic. Mathematical modeling is invaluable for informed biomedical HIV prevention research, policy and practice.

Department of Infectious Diseases, Cleveland Clinic Foundation, Cleveland, Ohio, USA

Correspondence to Ume L. Abbas, MD, Department of Infectious Diseases, Cleveland Clinic Foundation, 9500 Euclid Avenue/G21, Cleveland, OH 44195, USA Tel: +1 216 636 1873; e-mail:

Copyright © 2011 Wolters Kluwer Health, Inc. All rights reserved.