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Editorial introductions

Section Editor(s): Mohandas, Narla; Iruela-Arispe, M. Luisa

Current Opinion in Hematology: May 2019 - Volume 26 - Issue 3 - p v–vi
doi: 10.1097/MOH.0000000000000501

Current Opinion in Hematology was launched in 1994. It is part of a successful series of review journals whose unique format is designed to provide a systematic and critical assessment of the literature as presented in the many primary journals. The field of hematology is divided into nine sections that are reviewed once a year. Each section is assigned a Section Editor, a leading authority in the area, who identifies the most important topics at that time. Here we are pleased to introduce the Section Editors for this issue.

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Narla Mohandas

Dr Narla Mohandas is Vice President for Research at New York Blood Center, New York, USA. He received his doctoral degree from Washington University, St. Louis, USA in Chemical Engineering. After completing post-doctoral training in hematology research with Dr Marcel Bessis, Institute of Cellular Pathology in Paris, France, he joined the Faculty of Laboratory Medicine at University of California, San Francisco where he spent 13 years. In 1989, he moved to Lawrence Berkeley National Laboratory, University of California to head the Hematopoiesis group. During his 12-year tenure at the Berkeley Laboratory he also served as Interim Director of Human Genome Project for three years. In 2001, he moved to the New York Blood Center.

Dr Mohandas’ scientific interests during his 45-year research career have focused on red cell physiology and pathology. In particular, his efforts have contributed to improved understanding of the molecular and structural basis for red cell membrane disorders, developing detailed mechanistic insights into pathophysiology of thalassemias and sickle cell disease, characterizing structural and functional changes induced in red cells by the malarial parasite, plasmodium falciparum. His research efforts during last ten years are focused on molecular understanding of normal and disordered human erythropoiesis including Diamond-Blackfan anemia and Myelodysplasia.

Dr Mohandas served as a member of the National Institutes of Health Hematology study section for 18 years and is currently member of the NHLBI Advisory Council. He has been a member of numerous committees including the Executive committee of American Society of Hematology. He served as Associate Editor of Blood from 2003–2012 and is currently Editor-in-Chief of Blood Cells, Molecules and Disease and of Current Opinion in Hematology.

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M. Luisa Iruela-Arispe

Born in Spain, Dr M. Luisa Iruela-Arispe immigrated to South America at an early age attending school in Argentina and Brazil. She received her Ph.D. in 1989 and followed post-doctoral training at the University of Washington in Seattle, where she immersed herself is studies of extracellular matrix, atherosclerosis and angiogenesis, guided by giants in the field like Russel Ross, Paul Bornstein and Helene Sage. From 1994–1998 she served as Assistant Professor at Harvard Medical School and subsequently joined the faculty at University of California (UCLA), Los Angeles, California, USA in 1998.

At UCLA, Dr Iruela-Arispe ascended through the academic ranks and currently holds the title of Distinguished Professor in Molecular, Cell and Developmental Biology. In 2011 she was the first women to become Director of the Molecular Biology Institute which was founded by Nobel Prize winner Paul Boyer. She still leads the Institute and its prestigious graduate program. In addition, she serves as the Director of the Vascular Training Program at UCLA, which has been supported continuously by an NIH T32 award, now in its fourth iteration.

Throughout her career, Dr Iruela-Arispe performed research related to vascular biology in development and disease. Specifically, she has focused in elucidating the mechanisms that regulate the growth, specification and deregulation of vascular function during pathology. Along these lines, her laboratory has contributed to the literature of extracellular matrix proteins as regulators of angiogenesis; broadened knowledge on VEGF and Notch signaling, and evaluated the relevance of endothelial-hematopoietic cell interactions, including the discovery that hematopoietic progenitors emerge from the endothelium (hemogenic endothelium). More recently, her research has tackled the question of vascular regeneration and repair and the mechanisms involved in this process.

Dr Iruela-Arispe is actively engaged in teaching to undergraduate and graduate students. She provides instruction on Cell Biology to nearly 200 undergraduates every year at UCLA and teaches graduate courses on Scientific Writing and Vascular Biology. In 2009 she was recognized with the Distinguished Teaching Award for excellence in teaching and in 2013 she received the UCLA Gold Shield Faculty Prize, an accolade that recognizes one faculty member from the entire UCLA faculty in recognition of extraordinary accomplishments in undergraduate teaching, research and service. More recently, she received the post-doctoral mentoring award, which celebrates outstanding mentoring to post-doctoral fellows.

Dr Iruela-Arispe served as President of NAVBO (North American Vascular Biology Organization) and has remained an active participant in that organization. She is an Established Investigator of the American Heart Association and recipient of the inaugural Judah Folkman Award (2009). She has chaired two Gordon Conferences, several Keystone Meetings and the 2010 International Vascular Biology Meeting. Currently she serves in the Council for the National Heart and Lung Institute and the Advisory Board for the Intramural National Cancer Institute.

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