Current Opinion in Hematology was launched in 1994. It is part of a successful series of review journals whose unique format is designed to provide a systematic and critical assessment of the literature as presented in the many primary journals. The field of hematology is divided into nine sections that are reviewed once a year. Each section is assigned a Section Editor, a leading authority in the area, who identifies the most important topics at that time. Here we are pleased to introduce the Editor and the Section Editors for this issue.
Dr Narla Mohandas is Vice President for Research at New York Blood Center, USA. He received his doctoral degree from Washington University in St. Louis, USA, in Chemical Engineering. After completing post-doctoral training in hematology research with Dr Marcel Bessis, Institute of Cellular Pathology in Paris, France, he joined the faculty of the Department of Laboratory Medicine at University of California, USA, where he spent 13 years. In 1989, he moved to Lawrence Berkeley National Laboratory, University of California to head the Hematopoiesis group. During his 12 year tenure at the Berkeley Laboratory he also served as Interim Director of the Human Genome Project for three years. In 2001, he moved to the New York Blood Center, USA.
Dr Mohandas’ scientific interests have long focused on red cell physiology and pathology. In particular, his efforts have contributed to improved understanding of the molecular and structural basis for red cell membrane disorders, developing detailed mechanistic insights into pathophysiology of thalassemias and sickle cell anemia, characterizing structural and functional changes induced in red cells by the malarial parasite, plasmodium falciparum. His research efforts during the last five years have focused on molecular understanding of normal and disordered erythropoiesis including Diamond-Blackfan Anemia and Myelodysplasia.
Dr Mohandas served as a member of the National Institute of Health Hematology study section for 18 years and has been a member of numerous committees including the Executive committee of the American Society of Hematology. He served as Associate Editor of Blood from 2003–2012. He is currently Editor-in-Chief of Blood Cells, Molecules and Diseases and is on the Editorial Board of Biochemistry.
Edward F. Plow
Dr Plow received his PhD in Biochemistry in 1970. He joined The Scripps Research Institute, USA, as a postdoctoral fellow and remained at Scripps for 22 years, ultimately becoming a Full Member and Head of the Committee on Vascular Biology. In 1992, he relocated to the Cleveland Clinic, USA, to become Head of Research of the Joseph J. Jacobs Center for Thrombosis and Vascular Biology. He continues to hold this position and is Chair of the Department of Molecular Cardiology in the Lerner Research Institute of the Cleveland Clinic since 1994.
Throughout his career, Dr Plow has performed research related to thrombosis, hemostasis and vascular biology. A primary area of his research interests has been platelets and the mechanisms of their adhesive and aggregation responses. This research has led him to investigate integrin structure and function on blood and vascular cells. A primary emphasis of his current research is the molecules and mechanisms governing integrin activation, where he has been instrumental in showing that the kindlin family is critical for integrin function in model cells, mice and humans.
At the same time, Dr Plow has had a longstanding interest in the plasminogen system, with a particular emphasis on plasminogen and plasminogen receptors. The role of these molecules in cell adhesion, migration and inflammation has been emphasized. Recent studies by Dr Plow's group have touched into the areas of matrix biology and the roles of micro-RNAs in the pathogenesis of cardiovascular and neoplastic diseases.
Dr Plow was an Established Investigator of the American Heart Association and the recipient of the Distinguished Career award of the ISTH and of the Platelet Colloquium. He has chaired two Gordon Research Conferences and organized the ATVB Meeting of the AHA. He has chaired the Council of the ISTH and the ATVB Council of the AHA. He has received an honorary degree from the Medical University of Lodz, Poland; a ZiQiang Professorship of Shanghai University, China, and was elected a Fellow of the American Association of the Advancement of Science. Dr Plow is the 2014 recipient of the International Society of Fibrinolysis and Proteolysis Prize.