Meningeal Lymphatic vasculature in health and disease : Current Opinion in Hematology

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VASCULAR BIOLOGY: Edited by M. Luisa Iruela-Arispe

Meningeal Lymphatic vasculature in health and disease

Busch, Nishaa,∗; O’Reilly, Liama,∗; Louveau, Antoineb,c,d

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Current Opinion in Hematology 29(3):p 151-155, May 2022. | DOI: 10.1097/MOH.0000000000000711


Purpose of review 

The recent (re)discovery of the meningeal lymphatic has brought a new player in brain neurophysiology. This review highlights the state of the current research on the meningeal lymphatic vasculature, from its specific physiology to its increasing implication in normal and pathological brain function.

Recent findings 

Growing evidence are emerging about the uniqueness of the meningeal lymphatic vasculature and its implication in multiple neurological and neurotraumatic disorders.


These studies are highlighting a new and unexpected role for the lymphatic vasculature in brain function and a potential new therapeutic target for neurological disorders.

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