The 2019 guidelines from the American Society for Apheresis what's new?Connelly-Smith, Lauraa; Dunbar, Nancy M.bCurrent Opinion in Hematology: November 2019 - Volume 26 - Issue 6 - p 461–465 doi: 10.1097/MOH.0000000000000534 TRANSFUSION MEDICINE AND IMMUNOHEMATOLOGY: Edited by Steven L. Spitalnik Buy Abstract Author InformationAuthors Article MetricsMetrics Purpose of review For over 30 years, the American Society for Apheresis (ASFA) has published practice guidelines on the use of therapeutic apheresis in the Journal of Clinical Apheresis (JCA) Special Issue. These guidelines are periodically reviewed with the addition of new indications, retirement of some former indications and the provision of updated recommendations for current indications based on new published literature. During the last 12 years, updated guidelines have been published every 3 years to provide a reflection of current evidence-based apheresis practice. Recently, the eighth special issue was published. Significant updates and changes to the last edition are discussed in this review. Recent findings This review provides a description of the development of the eighth special issue with the evolution of the ASFA guidelines since introduced in 1986. There are no new indications for therapeutic apheresis listed in the 2019 edition, however, several recommended category changes to existing indications have been made. There are also several organizational changes with the renaming of some fact sheets. Summary ASFA has recently published its latest guidelines for therapeutic apheresis in the Journal of Clinical Apheresis ‘Eighth Special Edition’. This review describes the evolution of the ASFA guidelines and highlights significant changes to the prior edition. aDepartment of Medicine, Seattle Cancer Care Alliance & University of Washington, Seattle, Washington bDepartment of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA Correspondence to Nancy M. Dunbar, Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756-0001, USA. Tel: +1 603 650 5000; fax: +1 603 650 4845; e-mail: Nancy.M.Dunbar@hitchcock.org Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.