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Motility disorders of the colon and rectum

Wald, Arnold

Current Opinion in Gastroenterology: January 2012 - Volume 28 - Issue 1 - p 52–56
doi: 10.1097/MOG.0b013e32834d4f61
LARGE INTESTINE: Edited by Ciarán Kelly

Purpose of review The major motor functions of the large bowel include storage, propulsion and defecation. New developments continue to expand our knowledge of this area and provide significant advances in the treatment of disorders of colorectal motility.

Recent findings This article reviews new techniques to study colon motility and transit in health and constipation, recent published data which support the efficacy of novel and established laxatives for both functional and opioid-induced constipation, the development of neuromodulatory techniques for severe constipation and new insights into the pathogenesis and treatment of levator syndrome.

Summary The articles referenced in this review inform the reader of new developments in understanding and treating disorders of colonic and anorectal motility and anticipate future advances.

University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA

Correspondence to Arnold Wald, MD, University of Wisconsin School of Medicine and Public Health, Suite 4000, 1685 Highland Avenue, Madison, WI 53705, USA. Tel: +1 608 263 1995; e-mail:

© 2012 Lippincott Williams & Wilkins, Inc.