GASTROINTESTINAL INFECTIONS: Edited by Mark H. WilcoxTracking COVID-19 via sewageRooney, Christopher M.; Moura, Ines B.; Wilcox, Mark H.Author Information Leeds Institute of Medical Research, University of Leeds, Leeds, UK Correspondence to Mark H. Wilcox, Leeds Institute of Medical Research, HCAI Research Group, The Old Medical School, Leeds General Infirmary, Leeds LS1 3EX, UK. Tel: +44 113 392; e-mail: [email protected] Current Opinion in Gastroenterology: January 2021 - Volume 37 - Issue 1 - p 4-8 doi: 10.1097/MOG.0000000000000692 Buy Metrics Abstract Purpose of review We discuss the potential role of the faecal chain in COVID-19 and highlight recent studies using waste water-based epidemiology (WBE) to track severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Recent findings WBE has been suggested as an adjunct to improve disease surveillance and aid early detection of circulating disease. SARS-CoV-2, the aetiological agent of COVID-19, is an enveloped virus, and as such, typically not associated with the waste water environment, given high susceptibility to degradation in aqueous conditions. A review of the current literature supports the ability to detect of SARS-CoV-2 in waste water and suggests methods to predict community prevalence based on viral quantification. Summary The summary of current practices shows that while the isolation of SARS-CoV-2 is possible from waste water, issues remain regarding the efficacy of virial concentration and subsequent quantification and alignment with epidemiological data. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.