LARGE INTESTINE: Edited by Russell D. Cohen45 Is the new 50: improving colon cancer screening ratesLevy, Benjamin H. IIIa; Thelin, Camilleb; Da Silva, Julianac Author Information aDepartment of Medicine, Section of Gastroenterology, Hepatology and Nutrition, University of Chicago Medicine, University of Chicago, Chicago, Illinois bUSF Health Division of Digestive Diseases & Nutrition USF Women's Digestive Health, University of South Florida Gastroenterology Fellowship, Tampa, Floria cUniversity of Chicago, Chicago, Illinois, USA Correspondence to Benjamin H. Levy III, Clinical Associate, Section of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago Medicine, University of Chicago, Chicago, IL, USA. Tel: +1 404 375 5991; e-mail: [email protected] Current Opinion in Gastroenterology 39(1):p 31-35, January 2023. | DOI: 10.1097/MOG.0000000000000900 Buy Metrics Abstract Purpose of review The colonoscopy guidelines recently changed to begin screening at age 45. This review discusses the reasons for lowering the age, adenomatous polyp detection rates for patients 45–49, and to discover innovative health education campaigns aimed at younger patients. Recent findings There are currently approximately 20 million Americans between the age of 45–49 who will need to be screened by gastroenterologists. The prevalence of overall and advanced colorectal neoplasia on screening colonoscopy for average-risk individuals younger than 50 years is 14% and 2%. An important 2022 study using the GI Quality Improvement Consortium Registry demonstrated that patients aged 45–49 had an overall adenoma detection rate of >25%. Summary Health education campaigns need to immediately target 20 million Americans to begin colorectal cancer screening. Additional research should focus on whether there are sex differences for adenoma detection rates among patients aged 46–49. Innovative health education campaigns such as “Tune It Up: A Concert To Raise Colorectal Cancer” organized by the American College of Gastroenterology are educating younger patients to begin colorectal screening by combining concerts and health communication. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.