IMMUNOLOGY: Edited by Jocelyn A. SilvesterTreatment for eosinophilic esophagitisSyverson, Erin Phillips; Hait, Elizabeth J.Author Information Division of Gastroenterology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA Correspondence to Elizabeth J. Hait, MD, MPH, Division of Gastroenterology and Nutrition, Boston Children's Hospital, Harvard Medical School, Hunnewell Ground, 300 Longwood Ave, Boston, MA 02115, USA. Tel: +1 617 355 6058; e-mail: [email protected] Current Opinion in Gastroenterology: November 2020 - Volume 36 - Issue 6 - p 485-490 doi: 10.1097/MOG.0000000000000681 Buy Metrics Abstract Purpose of review To summarize current dietary and pharmacologic approaches in the treatment of eosinophilic esophagitis (EoE). Recent findings Studies comparing dietary approaches in EoE treatment support empiric elimination diets as the preferred approach to dietary EoE treatment, with no data to support use of currently available allergy tests to guide specific food elimination diets. Swallowed topical corticosteroid therapy is the current standard of care in pharmacologic EoE treatment, with similar effectiveness of fluticasone and budesonide, but their discontinuation results in return of both EoE symptoms and disease. A number of nonsteroid-based therapies are currently under investigation for the treatment of EoE, which are focused on targeting disease at a cellular level. Summary EoE can be treated with diet or medications. Empiric elimination is presently the preferred dietary approach. Swallowed steroids is the standard of care to treat EoE with medication; however, there are several promising drugs currently undergoing clinical trials. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.