Secondary Logo

Institutional members access full text with Ovid®

Population-based screening of hepatitis C virus in the United States

Bian, John; Schreiner, Andrew D.

Current Opinion in Gastroenterology: May 2019 - Volume 35 - Issue 3 - p 177–182
doi: 10.1097/MOG.0000000000000520
LIVER: Edited by Don C. Rockey

Purpose of review This review summarized the recent evidence on the performance of population-based hepatitis C virus (HCV) screening, published and indexed to PubMed, in the Unite States during the 2-year window from 1 January 2017 to 31 December 2018.

Recent findings A majority of the selected articles in this review focused on the birth cohort 1945–1965 because of the HCV screening recommendations released after August 2012. However, the articles for the high-risk population applied to all ages because the recommendations for this specific population have remained largely unchanged since 1998. The reported rates of HCV screening varied substantially not only across the three different populations (i.e. general, underserved, and high-risk) but also within each population.

Summary More vigilant monitoring of HCV screening performance of younger birth cohorts is needed as these individuals have been experiencing a higher incidence of HCV infection than those in the birth cohort 1945–1965. In addition, to meet the goal of eliminating HCV infection as a US public health problem by 2030, significant improvement in more accurately and comprehensively reporting the trends in population-based HCV screening across different populations is warranted in the future.

Department of Medicine, Medical University of South Carolina, Charleston, USA

Correspondence to John Bian, PhD, Associate Professor, Department of Medicine, Medical University of South Carolina, 135 Rutledge Avenue, Suite MSC 591, Charleston, SC 29425, USA. Tel: +1 843 876 7020; e-mail:

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.