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Indications of cholecystectomy in gallstone disease

Lamberts, Mark, P.

Current Opinion in Gastroenterology: March 2018 - Volume 34 - Issue 2 - p 97–102
doi: 10.1097/MOG.0000000000000419
BILIARY TRACT: Edited by Chantal Housset

Purpose of review Recent studies showed new insights in the indication and timing of cholecystectomy in gallstone disease. This review will provide an overview.

Recent findings Considerable variations in indication for gallbladder surgery have been noticed leading to a significant number of unnecessary cholecystectomies. As a consequence, up to 33% of patients with uncomplicated symptomatic gallstone disease have persistent abdominal pain after cholecystectomy. On the other hand, studies showed that certain patients with acute cholecystitis, common bile duct stones and biliary pancreatitis benefit from same admission instead of delayed cholecystectomy.

Summary A critical view on indications for cholecystectomy in patients with uncomplicated symptomatic gallstone disease prevents unnecessary cholecystectomies. In patients with mild-to-moderate complicated symptomatic gallstone disease, same-admission cholecystectomy reduces the risk of recurrent complications.

Department of Gastroenterology and Hepatology, Rijnstate Hospital, Arnhem, The Netherlands

Correspondence to Mark P. Lamberts, PhD, Rijnstate Hospital, PO Box 9555, 6800 TA Arnhem, The Netherlands. Tel: +31 26 3788888; fax: +31 88 0058853; e-mail:

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