THYROID: Edited by Angela M. LeungObesity as a risk factor for thyroid cancerMatrone, Antonio; Ferrari, Federica; Santini, Ferruccio; Elisei, RossellaAuthor Information Unit of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy Correspondence to Rossella Elisei, MD, Unit of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Via Paradisa, 2, 56124 Pisa, Italy. Tel: +39 050 544723; fax: +39 050 578772; e-mail: [email protected] Current Opinion in Endocrinology & Diabetes and Obesity: October 2020 - Volume 27 - Issue 5 - p 358-363 doi: 10.1097/MED.0000000000000556 Buy Metrics Abstract Purpose of review In this review, we evaluate recent findings related to the association between obesity and thyroid cancer. Recent findings During the last several decades, the prevalence of obesity and thyroid cancer have been increasing in parallel on a global scale. Current evidence suggests that the growing incidence of differentiated thyroid cancer (DTC) is pathogenically linked to the spread of obesity, but the biological mechanisms that may explain this connection have been only partially described. Furthermore, unlike other tumors, data on the impacts of obesity on the aggressiveness of DTC and response to treatment of DTC remain conflicting. Summary Emergent knowledge regarding the links between obesity and thyroid cancer suggests a relevant role for obesity as a risk factor for DTC, with no apparent impact on its aggressiveness. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.