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The clinical spectrum of adrenocortical hyperplasia

Schteingart, David E.

Current Opinion in Endocrinology & Diabetes and Obesity: June 2012 - Volume 19 - Issue 3 - p 176–182
doi: 10.1097/MED.0b013e3283537ee9
ADRENAL CORTEX: Edited by Ellen Seely

Purpose of review To describe the significance of a common adrenal radiological finding on computed tomography or MRI.

Recent findings Bilateral adrenocortical hyperplasia is the common expression of a variety of adrenal disorders, and its cause needs to be properly assessed in order to institute appropriate management.

Summary Behind the radiological finding of bilateral adrenal enlargement, there is a spectrum of diseases that require diagnostic evaluation and management. Many cases are benign and not associated with abnormalities of endocrine function. However, these abnormalities may develop years after the initial diagnosis has been made.

Division of Metabolism, Endocrinology and Diabetes, Endocrine Oncology Program, Department of Internal Medicine, University of Michigan, Michigan, USA

Correspondence to David E. Schteingart, MD, Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, Endocrine Oncology Program, University of Michigan, 1150 West Medical Center Drive, Room 5572 MSRB 2, Ann Arbor, MI 48109, USA. Tel: +1 734 615 9497; fax: +1 734 936 6684; e-mail:

© 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins