Obesity and nutrition: Edited by Caroline M. Apovian and Jeff I. MechanickBehavior therapy for obesity: where are we now?Sarwer, David Ba; von Sydow Green, Amya; Vetter, Marion La,b; Wadden, Thomas AaAuthor Information aDepartment of Psychiatry, Center for Weight and Eating Disorders, USA bDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA Correspondence to David B. Sarwer, PhD, Center for Weight and Eating Disorders, University of Pennsylvania School of Medicine, 3535 Market Street, Suite 3026, Philadelphia, PA 19104, USA Tel: +1 215 898 7314; fax: +1 215 898 2878; e-mail: email@example.com Current Opinion in Endocrinology, Diabetes and Obesity: October 2009 - Volume 16 - Issue 5 - p 347-352 doi: 10.1097/MED.0b013e32832f5a79 Buy Metrics Abstract Purpose of review To describe the short-term and long-term results of lifestyle modification for obesity. Recent findings Randomized controlled trials, which compared different diet and activity interventions were reviewed. Studies that investigated the efficacy of new technologies to provide lifestyle modification, such as web-based delivery, also were examined. Summary In general, comprehensive lifestyle modification programs delivered in person induce a loss of approximately 10% of initial weight in 16–26 weeks of treatment. The use of portion-controlled diets, which typically involve the use of meal replacement products, was associated with significantly larger weight losses in the short term. In contrast, interventions delivered via the Internet induced a loss of approximately 5%. However, web-based programs appear to have potential in facilitating the continuation on patient-provider contact, which along with high levels of physical activity, appear to be key strategies for successful long-term weight control. Recent studies also have suggested that the combination of lifestyle modification with long-term use of pharmacotherapy holds promise for maximizing initial weight losses and promoting long-term maintenance. © 2009 Lippincott Williams & Wilkins, Inc.