Neuroendocrinology: Edited by William H. LudlamPituitary stalk lesionsRupp, Demetra; Molitch, MarkAuthor Information Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA Correspondence to Mark Molitch, MD, Professor of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA Tel: +1 312 503 4130; e-mail: [email protected] Current Opinion in Endocrinology, Diabetes and Obesity: August 2008 - Volume 15 - Issue 4 - p 339-345 doi: 10.1097/MED.0b013e3283050844 Buy Metrics Abstract Purpose of review To describe the diverse causes of pituitary stalk lesions, their diagnosis, and treatment. Recent findings Pathology of the pituitary stalk is often distinct from disease processes that affect the hypothalamus and/or pituitary. Pituitary stalk lesions fall into one of three categories: congenital, inflammatory/infectious, and neoplastic lesions. Summary Stalk thickening may be found incidentally or when evaluating pituitary functional abnormalities. The precise cause must be looked for to enable the proper form of therapy of the underlying process. Hormone replacement is often also necessary. © 2008 Lippincott Williams & Wilkins, Inc.