CARDIOGENIC SHOCK: Edited by Fabio GuarracinoMechanical ventilation in cardiogenic shockTavazzi, Guidoa,b Author Information aUnit of Anaesthesia and Intensive Care, Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia bAnesthesia and Intensive Care, Fondazione Policlinico San Matteo Hospital IRCCS, Pavia, Italy Correspondence to Dr Guido Tavazzi, MD, PhD, Unit of Anaesthesia and Intensive Care, Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia; Anaesthesia, Intensive Care and Pain Therapy, Fondazione IRCCS Policlinico San Matteo, 1, Viale Golgi 19, 27100 Pavia, Italy. Tel: +39 0382 503711; fax: +39 0382 503008; e-mail: [email protected] Current Opinion in Critical Care: August 2021 - Volume 27 - Issue 4 - p 447-453 doi: 10.1097/MCC.0000000000000836 Buy Metrics Abstract Purpose of review Mechanical ventilation is frequently needed in patients with cardiogenic shock. The aim of this review is to summarize and discuss the current evidence and the pathophysiological mechanism that a clinician should consider while setting the ventilator. Recent findings Little attention has been placed specifically to ventilatory strategies in patients with cardiogenic shock undertaking mechanical ventilation. Lung failure in patients with cardiogenic shock is associated with worsening outcome as well as a delay in mechanical ventilation institution. The hemodynamic profile and cardiogenic shock cause, considering the preload dependency of the failing heart, must be defined to adjust ventilatory setting. Summary Evidence is growing regarding the role of lung failure as adverse prognostic factor and beneficial effect of positive pressure ventilation as part of first-line treatment in patients with cardiogenic failure. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.