CARDIOPULMONARY MONITORINGClinical use of peripheral perfusion parameters in septic shockBakker, Jana,b,c,dAuthor Information aDepartment of Intensive Care, Erasmus MC – University Medical Center, Rotterdam, The Netherlands bDepartment of Pulmonology and Critical Care, New York University NYU Langone Medical Center cDepartment of Pulmonology and Critical Care Columbia University Medical Center, New York USA dPontificia Universidad Católica de Chile, Department of Intensive Care, Santiago, Chile Correspondence to Jan Bakker, MD, PhD, Erasmus MC University Medical Center, Rotterdam, The Netherlands. E-mail: [email protected], [email protected] Current Opinion in Critical Care: June 2021 - Volume 27 - Issue 3 - p 269-273 doi: 10.1097/MCC.0000000000000826 Buy Metrics Abstract Purpose of review Current goals of resuscitation in septic shock are mainly a fixed volume of fluids and vasopressors to correct hypotension and improve tissue perfusion indicated by decreasing lactate levels Recent findings Abnormal peripheral perfusion by objective and subjective parameters are associated with increased mortality in various phases of the treatment of critically ill patients including patients with septic shock. Ongoing resuscitation in septic shock patients with normal peripheral perfusion is not associated with improved outcome, rather with increased mortality. Mitigation of fluid resuscitation by using parameters of peripheral perfusion in septic shock seems to be safe. Summary Septic shock patients with normal peripheral perfusion represent a different clinical phenotype of patients that might benefit from limited resuscitation efforts. Parameters of peripheral perfusion could be used to guide the individualization of patients with septic shock Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.