CARDIOPULMONARY RESUSCITATION: Edited by Fabio S. TacconeExtracorporeal cardiopulmonary resuscitation for cardiac arrestKalra, Rajata , *; Kosmopoulos, Marinosa , b , *; Goslar, Tomaza , b , c , *; Raveendran, Ganesha; Bartos, Jason A.a; Yannopoulos, DemetrisaAuthor Information aCardiovascular Division and Center for Resuscitation Medicine, University of Minnesota Medical School, Minneapolis, MN, USA bMedical Faculty, University of Ljubljana cCenter for Intensive Internal Medicine, University Medical Center Ljubljana, Slovenia Correspondence to Demetris Yannopoulos, MD, Center for Resuscitation Medicine, University of Minnesota Medical School, Minneapolis, MN 55401, USA. Tel: +1 612 626 1382; fax: +1 612 626 4411; e-mail: firstname.lastname@example.org Current Opinion in Critical Care: June 2020 - Volume 26 - Issue 3 - p 228-235 doi: 10.1097/MCC.0000000000000717 Buy Metrics Abstract Purpose of review Extracorporeal cardiopulmonary resuscitation (ECPR) is a contemporary resuscitation approach that employs veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This approach is increasingly used worldwide to mitigate the widespread hemodynamic and multiorgan dysfunction that accompanies cardiac arrest. Recent findings In this review, the physiology of VA-ECMO and ECPR, the role of ECPR in contemporary resuscitation care, the complications associated with ECPR and VA-ECMO usage, and intensive care considerations for this population are discussed. Summary ECPR offers a promising mechanism to mitigate multiorgan injury and allow time for the institution of supportive interventions required to effectively treat cardiac arrest. More prospective data in the context of extensive prehospital and hospital collaboration is needed to promote its successful use. Copyright © 2020 YEAR Wolters Kluwer Health, Inc. All rights reserved.