CARDIOPULMONARY RESUSCITATION: Edited by Bernd W. BöttigerTemperature management after cardiac arrestNielsen, Niklas; Friberg, Hans Author Information Department of Clinical Sciences, Section of Anesthesiology and Intensive Care, Lund University, Lund, Sweden Correspondence to Niklas Nielsen, MD, PhD, Intensive Care Unit, Helsingborg Hospital, S Vallgatan 5, 251 87 Helsingborg, Sweden. E-mail: [email protected] Current Opinion in Critical Care: June 2015 - Volume 21 - Issue 3 - p 202-208 doi: 10.1097/MCC.0000000000000203 Buy Metrics Abstract Purpose of review Temperature management for patients comatose after cardiac arrest has been an integral component of postcardiac arrest care for the last decade. In this review, we present recent findings and discuss implications for future trials. Recent findings The two largest trials on temperature management after cardiac arrest were recently presented. The first investigated prehospital induction of hypothermia using ice-cold intravenous saline in 1364 patients. The intervention gave a significant reduction in time from return of circulation to start of hypothermia and lower body temperature on admission to hospital. There was no difference in survival or neurological function between the study groups, but there were indications of possible harm in the group that received saline. The second trial investigated two actively controlled temperatures provided in intensive care units, randomizing 950 unconscious patients suffering out-of-hospital cardiac arrest of a presumed cardiac cause to targeted temperature management at 33 and 36°C. There was no difference in survival until end of trial or neurological function at 180 days. Summary Prehospital hypothermia induced by cold crystalloid infusion does not benefit cardiac arrest patients. For patients treated in an intensive care unit targeting a temperature of 36°C provides similar results as targeting 33°C. Copyright © 2015 YEAR Wolters Kluwer Health, Inc. All rights reserved.