HOT TOPICSafety of breast/chest-feeding by those infected by SARS-CoV-2Powell, Rebecca L.R. Author Information Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA Correspondence to Rebecca L.R. Powell, Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1090, New York, NY 10029, USA. E-mail: [email protected] Current Opinion in Clinical Nutrition and Metabolic Care: March 2022 - Volume 25 - Issue 2 - p 129-132 doi: 10.1097/MCO.0000000000000816 Buy Metrics Abstract Purpose of review One important question from the outset of the pandemic has been whether a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected person's milk might be a vehicle for SARS-CoV-2 transmission. This review summarizes the most recent data on this topic. Recent findings A SARS-CoV-2 sIgA response in milk after infection is very common. To date, there has been no evidence that SARS-CoV-2 transmits via human milk. Though viral RNA has been identified in a minority of milk samples studied, infectious virus particles have not. Summary The highly dominant transmission route for SARS-CoV-2 is via inhalation of respiratory droplets containing virus particles. Other routes of transmission are possible, including fecal–oral, trans-placental, and to a much lesser extent, via a contaminated surface. SARS-CoV-2 cannot transmit via human milk. There is no evidence that infants should be separated from SARS-CoV-2-infected mothers who are well enough to establish or continue breastfeeding. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.