Bioinformatics assistance of metabolic and nutrition management in the ICUBerger, Mette M; Que, Yok AiCurrent Opinion in Clinical Nutrition & Metabolic Care: March 2011 - Volume 14 - Issue 2 - p 202–208 doi: 10.1097/MCO.0b013e328341ed77 Nutrition and the intensive care unit: Edited by Mette Berger and Jeffrey I. Mechanick Abstract Author Information Purpose of review To review the domains in which computerized information systems have proven beneficial in facilitating the metabolic and nutritional management Recent findings In glucose control, computerized insulin algorithms have proven safer and more efficient than manual systems, reducing workload, time to target glycemia and numbers of hypoglycemic and hyperglycemic events. By rendering the nutritional variables visible through specific customization, computers do improve daily monitoring of energy balance and adherence to guidelines, particularly for substrate delivery. Nurse-centered systems have shown to be the most successful to enable routine workflow based on protocol-based care. Summary Computers are needed to analyze the increasing amount of data collected from critically ill patients from monitoring systems, laboratories and other sources. Studies have shown that computerized information systems do facilitate glucose control, helping reducing hypoglycemic events. They also improve nutritional monitoring (energy delivery and balance, protein and fat delivery), and quality of nutrition. They reduce nurse workload associated with the multiple balance calculations and ease visualization of events out of planned targets. Though integrated systems are expensive, they improve work efficiency. Service de Médecine Intensive Adulte et Centre des Brûlés, University Hospital, Rue du Bugnon 46, Lausanne, Switzerland Correspondance to Professor Mette M. Berger, Service de Médecine Intensive Adulte et Centre des Brûlés, CHUV-BH 08.612, Rue du Bugnon 46, CH - 1011 Lausanne, Switzerland Tel: +41 21 31 42 095; fax: +41 21 31 43 045; e-mail: Mette.Berger@chuv.ch © 2011 Lippincott Williams & Wilkins, Inc.