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Left ventricular function recovery after revascularization: comparative effects of percutaneous coronary intervention and coronary artery bypass grafting

Ngu, Janet M.C.a; Ruel, Marca; Sun, Louise Y.b , c

doi: 10.1097/HCO.0000000000000566
CORONARY ARTERY SURGERY: Edited by Marc Ruel

Purpose of review In 2013, heart failure with recovered ejection fraction (HFrecEF) was introduced as a new heart failure phenotype. This review provides an overview of HFrecEF and the comparative effects of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) on left ventricular ejection fraction (LVEF) recovery in patients with ischemic cardiomyopathy.

Recent findings There has been emerging data indicating that LV functional recovery is possible and HFrecEF is associated with improved survival and better quality of life. CABG may be associated with larger improvement in LVEF when compared with PCI. However, there is significant paucity of studies, which directly compare the impact of PCI and CABG on LVEF recovery in the setting of ischemic cardiomyopathy.

Summary LVEF recovery is emerging as an important outcome with demonstrated survival and quality-of-life benefits. Future randomized clinical trials comparing the impact of contemporary PCI and CABG on LVEF recovery are needed in patients with ischemic cardiomyopathy.

aDivision of Cardiac Surgery

bDivision of Cardiac Anesthesiology

cSchool of Epidemiology and Public Health, University of Ottawa, Ontario, Canada

Correspondence to Louise Y. Sun, MD, SM, FRCPC, Room H2410, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada. Tel: +1 613 696 7381; fax: +1 613 696 7099; e-mail: lsun@ottawaheart.ca

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