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Medication adherence: a key factor in achieving blood pressure control and good clinical outcomes in hypertensive patients

Krousel-Wood, Mariea,b,c; Thomas, Sheilaa; Muntner, Paulb,d; Morisky, Donalde

Current Opinion in Cardiology: July 2004 - Volume 19 - Issue 4 - p 357-362
doi: 10.1097/01.hco.0000126978.03828.9e
Hypertension

Purpose of review Patients’ adherence to antihypertensive drug regimens is a complex but important factor in achieving blood pressure control and reducing adverse cardiovascular outcomes. Approximately one half of patients with hypertension adhere to prescribed medications, and fewer than one in three patients have controlled blood pressure.

Recent findings Several recent studies have highlighted the importance of patient medication adherence and have outlined factors that affect patient compliance with prescribed therapy.

Summary On the basis of published studies, a conceptual framework of factors that affect patient adherence is presented. Recognizing patient nonadherence to medical therapy as a factor leading to poor blood pressure control and adverse outcomes remains a key challenge for clinicians caring for patients with hypertension.

aOchsner Clinic Foundation, New Orleans, Louisiana, the bDepartment of Epidemiology, Tulane University Health Sciences Center, New Orleans, Louisiana, the cDepartment of Family and Community Medicine, Tulane University Health Sciences Center, New Orleans, Louisiana, the dDepartment of Medicine, Tulane University Health Sciences Center, New Orleans, Louisiana, and the eDepartment of Community Health Sciences, UCLA School of Public Health, Los Angeles, California, USA

Correspondence to Marie A. Krousel-Wood, 1514 Jefferson Highway, New Orleans, LA 70121, USA

Tel: 504 842 3680; fax: 504 842 3648; e-mail: mawood@ochsner.org

© 2004 Lippincott Williams & Wilkins, Inc.