REVIEWDelirium in trauma ICUs: a review of incidence, risk factors, outcomes, and managementWilliams, Elliot C.a; Estime, Stephenb; Kuza, Catherine M.c Author Information aDepartment of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California bDepartment of Anesthesiology and Critical Care, University of Chicago Medicine, Chicago, Illinois cDepartment of Anesthesiology and Critical Care, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA Correspondence to Catherine M. Kuza, MD, FASA, FCCM, Department of Anesthesiology, 1450 San Pablo Street, Suite 3600, Los Angeles, CA 90033, USA. E-mail: [email protected] Current Opinion in Anaesthesiology ():10.1097/ACO.0000000000001233, January 05, 2023. | DOI: 10.1097/ACO.0000000000001233 Buy PAP Metrics Abstract Purpose of review This article reviews the impact and importance of delirium on patients admitted to the ICU after trauma, including the latest work on prevention and treatment of this condition. As the population ages, the incidence of geriatric trauma will continue to increase with a concomitant rise in the patient and healthcare costs of delirium in this population. Recent findings Recent studies have further defined the risk factors for delirium in the trauma ICU patient population, as well as better demonstrated the poor outcomes associated with the diagnosis of delirium in these patients. Recent trials and meta-analysis offer some new evidence for the use of dexmedetomidine and quetiapine as preferred agents for prevention and treatment of delirium and add music interventions as a promising part of nonpharmacologic bundles. Summary Trauma patients requiring admission to the ICU are at significant risk of developing delirium, an acute neuropsychiatric disorder associated with increased healthcare costs and worse outcomes including increased mortality. Ideal methods for prevention and treatment of delirium are not well established, especially in this population, but recent research helps to clarify optimal prevention and treatment strategies. Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.