ETHICS, ECONOMICS AND OUTCOME: Edited by Alice A. Tolbert CoombsDonation after circulatory death: opportunities on the horizonPotter, Kenneth F.a,b; Cocchiola, Brianb; Quader, Mohammed A.c Author Information aDivision of Critical Care Medicine bDepartment of Anesthesiology, Virginia Commonwealth University Health System cPauley Heart Center, Virginia Commonwealth University, Richmond, Virginia, USA Correspondence to Kenneth F. Potter, MD, 1200 East Broad Street, Box 980695, Richmond, VA 23298, USA. Tel: +804 628 3227; fax: +804 828 8300; e-mail: [email protected] Current Opinion in Anaesthesiology 34(2):p 168-172, April 2021. | DOI: 10.1097/ACO.0000000000000960 Buy Metrics Abstract Purpose of review Organ transplantation remains the gold standard therapy for many end-organ diseases. The demand for donor organs continues to grow to far exceed supply. This review summarizes recent protocols, procedures, and ethics surrounding the increased utilization of donors after circulatory death for transplantation. Recent findings An increasing number of centers are utilizing donation after circulatory death, and outcomes are improving. Although outcomes from donors after brain death continue to be the primary source of donation, circulatory death outcomes continue to improve approaching the level of brain death donors. Summary Donation after circulatory death offers a real opportunity to narrow the supply and demand issue with organ donation. Outcomes are improving, and protocols continue to evolve. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.