TRAUMA AND TRANSFUSION: Edited by Andrea U. SteinbickerPediatric non-red cell blood product transfusion practices: what's the evidence to guide transfusion of the ‘yellow’ blood products?Steinbicker, Andrea U.a; Wittenmeier, Evab; Goobie, Susan M.c Author Information aDepartment of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, University of Muenster, Muenster bDepartment of Anesthesiology, University Medicine of the Johannes Gutenberg-University Mainz, Mainz, Germany cDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA Correspondence to Susan M. Goobie, MD, FRCPC, Department of Anesthesiology, Critical Care and Pain Medicine, 300 Longwood Ave., Boston Children's Hospital, Boston, MA 02115, USA. E-mail: [email protected] Current Opinion in Anaesthesiology: April 2020 - Volume 33 - Issue 2 - p 259-267 doi: 10.1097/ACO.0000000000000838 Buy Metrics Abstract Purpose of review Research studies pertaining to the management of pediatric non-red cell blood product transfusion is limited. Clinical practices vary within disciplines and regions. Anesthesiologists need evidence-based guidelines to make appropriate and safe decisions regarding transfusion of the ‘yellow’ blood products for pediatric patients. Recent findings This review outlines clinical indications for transfusion of fresh frozen plasma, cryoprecipitate, platelets, and fibrinogen concentrate in pediatrics. Recent studies of non-red blood cell transfusions in critical, but stable situations are highlighted. Recommendations to guide transfusion of the ‘yellow’ blood products in operative and non-operative settings are summarized. Special attention is drawn to guidelines in massive hemorrhage and trauma situations. Summary Evidence-based guidelines and expert consensus recommendations exist to guide the transfusion of pediatric non-red blood products and should be followed when transfusing the ‘yellow’ blood components. As high-quality studies in neonates, infants and children are limited, future research should broaden our knowledge in this direction with the goal to use restrictive strategies to improve patient outcomes. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.