OBSTETRIC AND GYNECOLOGICAL ANESTHESIA: Edited by Andreas HoeftAnesthetic consideration for neuromuscular diseasesKatz, Jeffery A.; Murphy, Glenn S.Author Information Northshore University Health System, University of Chicago, Pritzker School of Medicine, Illinois, USA Correspondence to Glenn S. Murphy, Northshore University Health System, University of Chicago, Pritzker School of Medicine, IL 60201, USA. Tel: +1 773 259 4322; e-mail: [email protected] Current Opinion in Anaesthesiology: June 2017 - Volume 30 - Issue 3 - p 435-440 doi: 10.1097/ACO.0000000000000466 Buy Metrics Abstract Purpose of review The aim of this review is to examine data relating to perioperative management of the patient with neuromuscular disorders Recent findings Patients with pre-existing neuromuscular disorders are at risk for a number of postoperative complications that are related to anesthetic drugs that are administered intraoperatively. Careful preoperative assessment is necessary to reduce morbidity and mortality. In particular, the risk of postoperative respiratory failure and need for long-term ventilation should be reviewed with patients. The use of succinylcholine should be avoided in muscular dystrophies, motor neuron diseases, and intrinsic muscle disease due to a risk of malignant hyperthermia, hyperkalemia, rhabdomyolysis, and cardiac arrest. The use of quantitative neuromuscular monitoring should be strongly considered whenever nondepolarizing neuromuscular blocking agents are administered. A number of case series and reports have been recently published demonstrating that sugammadex can be safely used in patients with neuromuscular disease; the risk of residual neuromuscular is nearly eliminated when this agent is administered intraoperatively. Summary Careful assessment and management of patients with underlying neuromuscular diseases is required to reduce postoperative complications. This article reviews the anesthetic implications of patients undergoing surgery with neuromuscular disorder. Copyright © 2017 YEAR Wolters Kluwer Health, Inc. All rights reserved.