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Central venous pressure: soon an outcome-associated matter

Sondergaard, Soren; Parkin, Geoffrey; Aneman, Anders

Current Opinion in Anaesthesiology: April 2016 - Volume 29 - Issue 2 - p 179–185
doi: 10.1097/ACO.0000000000000305

Purpose of review Central venous pressure (CVP) alone has so far not found a place in outcome prediction or prediction of fluid responsiveness. Improved understanding of the interaction between mean systemic pressure (Pms) and CVP has major implications for evaluating volume responsiveness, heart performance and potentially patient outcomes.

Recent findings The literature review substantiates that CVP plays a decisive role in causation of operative haemorrhage and renal failure. The review details CVP as a variable integral to cardiovascular control in its dual role of distending the diastolic right ventricle and opposing venous return.

Summary The implication for practice is in the regulation of the circulation. It is demonstrated that control of the blood pressure and cardiac output/venous return calls upon regulation of the volume state (Pms), the heart performance (Eh) and the systemic vascular resistance. Knowledge of the CVP is required to calculate all three.

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aCentre of Elective Surgery, Silkeborg Regional Hospital, Denmark

bIntensive Care Unit, Monash Medical Centre, Clayton, Victoria

cIntensive Care Unit, Liverpool Hospital, SWSLHD, Liverpool BC

dSydney Western Clinical School, University of New South Wales, New South Wales, Australia

Correspondence to Soren Sondergaard, PhD, Centre of Elective Surgery, Silkeborg Regional Hospital, Denmark. Tel: +45 5122 3082; e-mail:

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