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Novel approaches in pain management in cardiac surgery

Bigeleisen, Paul E.; Goehner, Nicholas

Current Opinion in Anaesthesiology: February 2015 - Volume 28 - Issue 1 - p 89–94
doi: 10.1097/ACO.0000000000000147

Purpose of review Open cardiac surgery may cause severe postoperative pain and the activation of a perioperative stress response. If not treated adequately, the patient may suffer increased morbidity, a longer hospital stay, and higher overall costs. This article reviews the literature regarding various modalities for management of postoperative pain after cardiac surgery.

Recent findings Paravertebral block of the spinal nerve roots provides similar analgesia to thoracic epidural without the risk of hypotension or epidural hematoma. Continuous α-2 agonist infusion reduces opioid requirements in the immediate postoperative period and may convey a morbidity and mortality benefit in cardiac surgery patients that persists for 12 months. Antiepileptics may significantly decrease opioid requirements and improve pain scores. Finally, complementary and alternative practices such as acupuncture, music, and behavioral exercises both pre and postoperatively may improve acute pain and lessen conversion to chronic pain.

Summary Although published data remain limited, recent evidence indicates that patients may benefit from the addition of a variety of novel pain-management strategies currently under investigation. Selection of a multimodal approach to perioperative pain management is advocated, including selective application of regional analgesia, non-narcotic medications, and complimentary alternative options to improve patient comfort and overall outcome.

Department of Anesthesiology and Critical Care, University of Maryland School of Medicine, Baltimore, Maryland, USA

Correspondence to Paul E. Bigeleisen, Department of Anesthesiology and Critical Care, University of Maryland School of Medicine, 22 S Greene St S11C00, Baltimore, MD 21201-1544, USA. Tel: +1 410 328 6720; fax: +1 410 328 5531; e-mail:

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