Premedication of the pediatric patient – anesthesia for the uncooperative childBozkurt, PervinCurrent Opinion in Anaesthesiology: June 2007 - Volume 20 - Issue 3 - p 211–215 doi: 10.1097/ACO.0b013e328105e0dd Paediatric anaesthesia Abstract Author InformationAuthors Article MetricsMetrics Purpose of review Inadequate handling of an uncooperative child preoperatively results in postoperative behavior problems. Premedication enables a calm induction and helps to decrease postoperative problems. Several premedicants will be covered in this review. Recent findings Questions raised about the effects of oral midazolam use in children for premedication are now finding answers. New agents (dexmedetomidine and atypical antipsychotic agents) can be alternatives in premedication, especially in severely uncooperative children. The current literature highlights the missing information about the rather older premedicants. Summary The benefits and disadvantages of new and older drugs should be weighed against each other, and decisions should be made according to the requirements of surgery, ward conditions and the severity of psychologic, developmental or mental disease. Further studies for the evaluation of the anxiolytic, sedative and antipsychotic drugs are still required. Department of Anesthesiology and Reanimation, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey Correspondence to Pervin Bozkurt, Department of Anesthesiology and Reanimation, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey Tel: +90 5325946527; fax: +90 212 4143589; e-mail: email@example.com, firstname.lastname@example.org © 2007 Lippincott Williams & Wilkins, Inc.