Ethics, economics and outcomeEthics in researchBevan, Joan CAuthor Information Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada Correspondence to Joan C. Bevan, MD, MHSc, FRCA, Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada Current Opinion in Anaesthesiology: April 2007 - Volume 20 - Issue 2 - p 130-136 doi: 10.1097/ACO.0b013e328014a833 Buy Metrics Abstract Purpose of review This review will examine research ethics in the context of globalization of clinical trials and recent rapid developments in bioscience. It will focus on international ethical guidelines and the functions of research ethics review boards in research governance. Consent issues in genetic research, which must comply with privacy laws by protecting confidentiality and privacy of personal health data, will be discussed. Recent findings There has been a rapid expansion of genomic and proteonomic research and biotechnology in the last decade. International ethical guidelines have been updated and the bioscience industry has developed ethics policies. At the same time, problems in academic anesthesia in the US and UK have been identified, leading to recommendations to train physician-scientists in anesthesia to stimulate research activity in the future. Anesthesiologists are joining interdisciplinary research teams and the concept of evidence-based translational research is emerging. Summary Anesthesiologists are moving towards participation in interdisciplinary research teams. They are well placed to speed the translation of research discovery into clinical practice and provide evidence-based perioperative care. This review provides the ethical framework that anesthesiologists will need to meet the challenges of this changing pattern of practice. © 2007 Lippincott Williams & Wilkins, Inc.