REVIEWApplying the new guidelines to asthma management in childrenCastagnoli, Riccardoa,b,∗; Brambilla, Ilariaa,b,∗; Giudice, Michele Miraglia Delc; Marseglia, Gian Luigia,b; Licari, Ameliaa,b Author Information aPediatric Unit, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia bPediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia cDepartment of Woman, Child and General and Specialized Surgery, University of Campania ‘Luigi Vanvitelli’, Napoli, Italy Correspondence to Professor Gian Luigi Marseglia, Pediatric Unit, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Fondazione IRCCS Policlinico San Matteo, p.le Golgi 19, 27100 Pavia, Italy. Tel: +390382502818; e-mail: [email protected] Current Opinion in Allergy and Clinical Immunology ():10.1097/ACI.0000000000000892, January 13, 2023. | DOI: 10.1097/ACI.0000000000000892 Buy PAP Metrics Abstract Purpose of review This review aims to provide paediatricians with novel concepts from scientific evidence applicable to treating children with asthma. The latest guideline updates on paediatric asthma are discussed here, with a focus on the 2022 update of the GINA document. Recent findings Mild asthma remains to be an important challenge for the paediatrician, and the introduction of new evidence-based treatment strategies, particularly those symptom-driven, could have a significant impact on the paediatric population. The identification of predictive biomarkers, the definition of biological treatment response, the possible duration of these therapies in this age group, as well as their potential action on airway remodelling are desirable in the short term. As the number of available biological treatment options expands, paediatricians should be supported by further evidence in decision-making. Summary There is an urgent need to implement at multiple levels the latest therapeutic strategies proposed for asthma at all severities. Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.