Allergic manifestations of contact lens wearingSolomon, AbrahamCurrent Opinion in Allergy and Clinical Immunology: October 2016 - Volume 16 - Issue 5 - p 492–497 doi: 10.1097/ACI.0000000000000311 EYE ALLERGY: Edited by Leonard Bielory and Abraham Solomon Buy Abstract Author InformationAuthors Article MetricsMetrics Purpose of review Contact lens-induced papillary conjunctivitis (CLPC) is a common ocular allergic disease in contact lens wearers. In its more severe form, it can cause giant papillary conjunctivitis, resulting in contact lens intolerance and the need to discontinue the use of contact lenses. This review presents the pathogenesis, clinical manifestations and management guidelines of this common disorder. Recent findings Different types of contact lenses are associated with differences in the severity of CLPC. Refitting patients with silicone hydrogel contact lenses or with daily disposable contact lenses may improve the signs and symptoms of CLPC. The recent introduction of the topical immunomodulatory agent tacrolimus in other severe allergic eye diseases may apply in suppressing the allergic inflammation in CLPC as well. Summary CLPC is a common ocular disorder in contact lens wearers, with a significant impact on the quality of vision. It should be promptly recognized by healthcare practitioners and managed by modifications of the types and wearing schedules of contact lenses, as well as novel treatment options with topical immunomodulators. Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel Correspondence to Abraham Solomon, MD, Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel. E-mail: email@example.com Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.