PEDIATRIC ASTHMA AND DEVELOPMENT OF ATOPY: Edited by Carlos E. Baena-Cagnani and Leonard B. BacharierChildhood asthma and chronic obstructive pulmonary disease outcomes until the age of 50Tai, Andrew Author Information aDepartment of Respiratory and Sleep Medicine, Women's and Children's Hospital, North Adelaide bUniversity of Adelaide, South Australia, Australia Correspondence to Dr Andrew Tai, Department of Respiratory and Sleep Medicine, Women's and Children's Hospital, 72 King William Road, North Adelaide, SA 5006, Australia. Tel: +618 8161 7234; fax: +618 8161 9192; e-mail: [email protected] Current Opinion in Allergy and Clinical Immunology: April 2015 - Volume 15 - Issue 2 - p 169-174 doi: 10.1097/ACI.0000000000000146 Buy Metrics Abstract Purpose of review There has been recent interest in understanding the origins of chronic obstructive pulmonary disease. Epidemiological studies suggest that chronic obstructive pulmonary disease clearly has other causes apart from tobacco smoke. Recent findings Cross-sectional studies of adult cohorts with chronic obstructive pulmonary disease highlight that childhood asthma is a risk factor. A recent longitudinal childhood cohort study of children from childhood to the age of 50 years describes that children with severe asthma are at increased risk of chronic obstructive pulmonary disease and that the deficit in lung function can be tracked back to early years. Summary Children with severe asthma are at increased risk of developing chronic obstructive pulmonary disease. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.