Outcome measuresTreatment with inhaled corticosteroids improves pulmonary function in children under 2 years old with risk factors for asthmaTeper, Alejandro Manuel; Kofman, Carlos DanielAuthor Information Respiratory Center, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina Correspondence to Alejandro Manuel Teper MD, Vidt 1956 Piso 1, (1425) Buenos Aires, Argentina Tel/fax: +54 11 4966 1015; e-mail: email@example.com Current Opinion in Allergy and Clinical Immunology: June 2006 - Volume 6 - Issue 3 - p 152-154 doi: 10.1097/01.all.0000225151.99284.cd Buy Metrics Abstract Purpose of review To report on recent studies on the effect of inhaled corticosteroids on pulmonary function in young children with asthma. Recent findings Inhaled corticosteroids are considered the most effective treatment for persistent asthma in children. Appropriate control of childhood asthma may prevent more serious disease or irreversible obstruction in later years. While some authors have described an improvement with the use of inhaled corticosteroids in young children, others found no clinical or functional benefit. Various studies have shown that inhaled corticosteroids ameliorate clinical outcomes, and recently a study demonstrated improvement in pulmonary function in young children with asthma. The use of different study designs may explain the lack of consistent results and disagreement regarding the efficacy of inhaled corticosteroids in these patients. Summary Based on the preponderance of evidence, treatment with inhaled corticosteroids in infants and young children with recurrent wheeze and risk factors of developing asthma appears to allow better control of the illness and improve the pulmonary function. Copyright © 2006 Wolters Kluwer Health, Inc. All rights reserved.