Chinese Medical Journal
Lung cancer is among the most common malignant tumors that cause serious harm to humans. Despite the successes of chemotherapy, radiotherapy, and targeted therapy, the prognosis of lung cancer remains unsatisfactory. Fortunately, patients with lung cancer have found hope in immunotherapy, particularly, in immune checkpoint inhibitors (ICIs). ICIs in immunotherapy for lung cancer have shifted from back-line treatment to first-line treatment, from palliative treatment to consolidation treatment, from advanced lung cancer therapy to early neoadjuvant therapy, and towards precise individualized treatment. However, immunotherapy involves many problems that should be considered and resolved. This collection focuses on the recent advancements and challenges of ICIs in patients with lung cancer.