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HIV-AIDS

  • Creator:   Chinese Medical Journal
  • Updated:   6/22/2021
  • Contains:  8 items
Acquired immunodeficiency syndrome (AIDS) is a chronic, potentially life-threatening condition caused by the human immunodeficiency virus (HIV). By damaging your immune system, HIV interferes with your body's ability to fight infection and disease. HIV is a sexually transmitted infection (STI). It can also be spread by contact with infected blood or from mother to child during pregnancy, childbirth or breast-feeding. Without medication, it may take years before HIV weakens your immune system to the point that you have AIDS. There's no cure for HIV/AIDS, but medications can dramatically slow the progression of the disease.

Public health significance of human immunodeficiency virus pre-exposure and post-exposure prophylaxis

Xu, Jun-Jie; Shang, Hong

Chinese Medical Journal. 133(23):2773-2774, December 5, 2020.

Highlight: While addressing the expansion of HIV testing and early ART for PLWHIV, we should fully consider the role of PrEP and nPEP and integrate them into a comprehensive HIV prevention and control strategies in China to effectively promote HIV prevention and control and reduce the epidemic of HIV infection in key populations in China.

Advances and challenges in antiretroviral therapy for acquired immunodeficiency syndrome

Bai, Ruo-Jing; Dai, Li-Li; Wu, Hao

Chinese Medical Journal. 133(23):2775-2777, December 5, 2020.

Highlight: During the past forty years, concerns about advances of ART revolutionized HIV has been in existence. Before the arrival of a cure for HIV, future research needs to be oriented with the improvement of the efficacy, securities, conveniences, as well as equitable level of ART for all of the HIV people. The current growth of novel ARV agents is required to enhance the HIV treatment cascade, which aims to upgrade PLWH's lives in the meanwhile of lowering the secondary transmission and striving to bring the HIV epidemic to the end around the world.

Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China

Zhang, Jing; Xu, Jun-Jie; Chu, Zhen-Xing; More

Chinese Medical Journal. 133(23):2778-2786, December 5, 2020.

Highlight: College student MSM had higher proportion of HIV recent infection and TDR than the youth and older MSM in China during 2012-2013. The HIV infections were more likely to happen during the early year of college life among student MSM

Clinical features and treatment outcomes of human immunodeficiency virus-associated cryptococcal meningitis: a 2-year retrospective analysis

Song, Wei; Shen, Yin-Zhong; Wang, Zhen-Yan; More

Chinese Medical Journal. 133(23):2787-2795, December 5, 2020.

Highlight: Clinical features and outcomes of first diagnosed HIV-associated CM with 2-year follow-up data. Altered mental status and coinfection with PCP predicted mortality in HIV-associated CM.

Clinical outcomes of people living with human immunodeficiency virus (HIV) with diffuse large B-cell lymphoma (DLBCL) in Shanghai, China

Sun, Jian-Jun; Liu, Li; Wang, Jiang-Rong; More

Chinese Medical Journal. 133(23):2796-2802, December 5, 2020.

Highlight: Outcomes of R-CHOP therapy do not differ from those of DA-EPOCH-R therapy. No HIV-related factors were found to be associated with the OS of PLHIV in the modern cART era.

Advances in research of HIV transmission networks

Dong, Zhi-Long; Gao, George Fu; Lyu, Fan

Chinese Medical Journal. 133(23):2850-2858, December 5, 2020.

Highlight: We established a systematic review of these aforementioned transmission networks with respect to their definitions, applications, limitations, recent progress, and synthetic applications.

Asymptomatic cryptococcal antigenemia in HIV-infected patients: a review of recent studies

Xu, Xiao-Lei; Zhao, Ting; Harypursat, Vijay; More

Chinese Medical Journal. 133(23):2859-2866, December 5, 2020.

Highlight: Early screening and optimized preemptive treatment for ACA is likely to help decrease the incidence of cryptococcosis, and is lifesaving. Further studies are warranted to explore issues related to the optimal management of ACA

Heterogeneity of HIV-1 latent reservoirs

Zhao, Jia-Cong; Deng, Kai

Chinese Medical Journal. 133(23):2867-2873, December 5, 2020.

Highlight: We discuss the different cell types and mechanisms contributing to the complexity and heterogeneity of HIV-1 latent reservoirs, and summarize the key challenges to the development of cure strategies for acquired immunodeficiency syndrome (AIDS).