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Prevalence and Impact on Mechanical Ventilation Weaning of Pleural Effusion in ICU Patients

Dres, Martin MD, PhD*,†; Razazi, Keyvan MD‡,§

doi: 10.1097/CPM.0000000000000324
Critical Care/Respiratory Care

Pleural effusion is frequently encountered in patients who are mechanically ventilated in the intensive care unit and may be logically suspected in case of difficult weaning from mechanical ventilation. Through several mechanisms, pleural effusion may impair gas exchange, respiratory mechanics, and ventilation/perfusion matching. However, data exploring the respective contribution of pleural effusion on weaning failure are scarce. This review discusses the most recent findings pertaining to the potential role of pleural effusion in weaning outcome.

*Sorbonne Université, INSERM, UMRS1158 Neurophysiologie respiratoire expérimentale et clinique

AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pneumologie, Médecine Intensive—Réanimation (Département “R3S”), Paris

AP-HP, Hôpitaux universitaires Henri Mondor, DHU A-TVB, Service de Réanimation Médicale

§Université Paris Est Créteil, Faculté de Médecine de Créteil, IMRB, GRC CARMAS, Créteil, France

Disclosure: M.D. received personal fees for expertise from Lungpacer. K.R. declares that there is no conflicts of interest.

Address correspondence to: Martin Dres, MD, PhD, Service de Pneumologie, Médecine Intensive—Réanimation, Groupe Hospitalier Pitié-Salpêtrière, 47-83 Boulevard de l’Hôpital, Cedex 13, Paris 75651, France. E-mail:

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