Pleural effusion is frequently encountered in patients who are mechanically ventilated in the intensive care unit and may be logically suspected in case of difficult weaning from mechanical ventilation. Through several mechanisms, pleural effusion may impair gas exchange, respiratory mechanics, and ventilation/perfusion matching. However, data exploring the respective contribution of pleural effusion on weaning failure are scarce. This review discusses the most recent findings pertaining to the potential role of pleural effusion in weaning outcome.
*Sorbonne Université, INSERM, UMRS1158 Neurophysiologie respiratoire expérimentale et clinique
†AP-HP, Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service de Pneumologie, Médecine Intensive—Réanimation (Département “R3S”), Paris
‡AP-HP, Hôpitaux universitaires Henri Mondor, DHU A-TVB, Service de Réanimation Médicale
§Université Paris Est Créteil, Faculté de Médecine de Créteil, IMRB, GRC CARMAS, Créteil, France
Disclosure: M.D. received personal fees for expertise from Lungpacer. K.R. declares that there is no conflicts of interest.
Address correspondence to: Martin Dres, MD, PhD, Service de Pneumologie, Médecine Intensive—Réanimation, Groupe Hospitalier Pitié-Salpêtrière, 47-83 Boulevard de l’Hôpital, Cedex 13, Paris 75651, France. E-mail: firstname.lastname@example.org.