Respiratory InfectionsShould the ATS/IDSA Guidelines for Hospital-acquired and Ventilator-associated Pneumonia be Reevaluated?Ferrer, Miquel MD*,†; Li Bassi, Gianluigi MD*,†; Saucedo, Lina Maria MD*; Torres, Antoni MD*,†Author Information *Servei de Pneumologia, Institut Clinic del Torax, Hospital Clinic, Institut d' Investigacions Biomèdiques Agust Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona †Centro de Investigación Biomedica En Red, Enfermedades Respiratorias, Instituto de Salud Carlos III, Ministerio de Ciencia e Innovacion, Madrid, Spain Supported by IDIBAPS, CibeRes (CB06/06/0028)-ISCiii, and 2009 SGR 911. Address correspondence to: Miquel Ferrer, MD, Servei de Pneumologia, Institut del Torax, Hospital Clı´nic, Villarroel 170, 08036 Barcelona, Spain. e-mail: [email protected]. Clinical Pulmonary Medicine: January 2011 - Volume 18 - Issue 1 - p 8-13 doi: 10.1097/CPM.0b013e318203720e Buy Metrics Abstract We have revised the effects of implementing the current and former guidelines for the management and treatment of ventilator-associated pneumonia (VAP) on the outcome of intensive care unit patients, with particular focus on issues related to VAP etiology, pathogen prediction, appropriate empiric antibiotic therapy, and mortality. Several studies showed that in patients with clinical suspicion of VAP, appropriate antibiotic therapy administered in a timely manner could improve survival. The guidelines for the management and treatment of VAP have been developed to help physicians achieve these goals. Implementation of these guidelines into clinical practice is difficult to achieve and requires extensive education for healthcare personnel and translation of recommendations into local protocols. Studies have shown that guideline implementation is associated with better outcome. However, extensive research needs to be undertaken to validate the efficacy of guidelines in predicting the etiology of pneumonia, in particular, to promptly identify multidrug-resistant pathogens. A recent report has validated the latest guidelines and has called attention for further research to improve microbial prediction. © 2011 Lippincott Williams & Wilkins, Inc.