The addition of nocturnal noninvasive positive pressure ventilation to pulmonary rehabilitation in patients with chronic obstructive pulmonary disease and chronic respiratory failure produced improvements in measures of health-related quality of life, functional status, and gas exchange.
Duiverman ML, Wempe JB, Bladder G, et al. Nocturnal noninvasive ventilation in addition to rehabilitation in hypercapnic patients with COPD. Thorax. 2008;93:1052–1057.