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Cystic and Solid Brain Metastases in a Patient With Small Cell Lung Carcinoma

Balasubramanian, Vijay P. MD*‡; Kocak, Mehmet MD†§; Schapira, Ralph M. MD, FCCP*‡

doi: 10.1097/01.cpm.0000187184.87562.fa
Images in Pulmonary Medicine
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Brain metastases occur in 25%–35% of all cancer patients. The majority of brain metastases are solid tumors; cystic brain metastases are unusual. Several reports of cystic brain metastases associated with non–small cell lung carcinoma have been described, but small cell lung carcinoma presenting with cystic brain metastases is previously unrecognized. We encountered a patient with biopsy-proven small cell lung carcinoma with cystic metastatic lesions in the brain, also due to small cell lung carcinoma. These metastatic lesions were associated with significant neurologic findings and required drainage of the cysts. The frequency, clinical presentations, and imaging findings of cystic metastatic lesions within the brain are reviewed.

We encountered a patient with biopsy-proven small cell lung carcinoma with cystic metastatic lesions in the brain, also due to small cell lung carcinoma. The frequency, clinical presentations, and imaging findings of cystic metastatic lesions within the brain are reviewed.

From the *Division of Pulmonary and Critical Care Medicine and †Department of Radiology, Medical College of Wisconsin, Milwaukee, WI; and the ‡Zablocki Veterans Affairs Medical Center, §Section of Radiology (Dr. Kocak), Milwaukee, WI.

Address correspondence to: Ralph M. Schapira, MD, FCCP, Zablocki Veterans Affairs Medical Center, 5000 West National Avenue (CC-111), Milwaukee, WI 53295. E-mail: rschapir@mail.mcw.edu.

© 2005 Lippincott Williams & Wilkins, Inc.